Cardiac output and cerebral blood flow: the integrated regulation of brain perfusion in adult humans

L Meng, W Hou, J Chui, R Han, AW Gelb - Anesthesiology, 2015 - pubs.asahq.org
Cerebral blood flow (CBF) is rigorously regulated by various powerful mechanisms to
safeguard the match between cerebral metabolic demand and supply. The question of how …

Cerebral blood flow impairment and cognitive decline in heart failure

A Ovsenik, M Podbregar, A Fabjan - Brain and Behavior, 2021 - Wiley Online Library
Abstract Background and Purpose Cognitive decline is an important contributor to disability
in patients with chronic heart failure, affecting 25%–50% of patients. The aim of this review is …

Heart failure and Alzheimer′ s disease

P Cermakova, M Eriksdotter, LH Lund… - Journal of internal …, 2015 - Wiley Online Library
It has recently been proposed that heart failure is a risk factor for Alzheimer′ s disease.
Decreased cerebral blood flow and neurohormonal activation due to heart failure may …

Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

GA Fulop, S Tarantini… - American Journal …, 2019 - journals.physiology.org
There has been an increasing appreciation of the role of vascular contributions to cognitive
impairment and dementia (VCID) associated with old age. Strong preclinical and …

Reduced regional cerebral blood flow in patients with heart failure

B Roy, MA Woo, DJJ Wang… - European journal of …, 2017 - Wiley Online Library
Aims Heart failure (HF) patients show significant lateralized neural injury, accompanied by
autonomic, mood and cognitive deficits. Both gray and white matter damage occurs and …

Cognitive impairment in heart failure—a review

FQ Goh, WKF Kong, RCC Wong, YF Chong… - Biology, 2022 - mdpi.com
Simple Summary Compared to the general population, patients with heart failure have
reduced cognition and increased dementia risk. Brain changes have been observed in …

Cognitive impairments in chronic heart failure: a case controlled study

MJ Sauvé, WR Lewis, M Blankenbiller… - Journal of cardiac …, 2009 - Elsevier
BACKGROUND: There are limited data describing the prevalence, type, and severity of
cognitive impairments (CIs) in the general population with chronic heart failure (HF). The …

The adverse effects of reduced cerebral perfusion on cognition and brain structure in older adults with cardiovascular disease

ML Alosco, J Gunstad, BA Jerskey, X Xu… - Brain and …, 2013 - Wiley Online Library
Background It is well established that aging and vascular processes interact to disrupt
cerebral hemodynamics in older adults. However, the independent effects of cerebral …

Cerebral perfusion is associated with white matter hyperintensities in older adults with heart failure

ML Alosco, AM Brickman, MB Spitznagel… - Congestive heart …, 2013 - Wiley Online Library
Cognitive impairment is common in heart failure (HF) and believed to be the result of
cerebral hypoperfusion and subsequent brain changes including white matter …

Atrial fibrillation exacerbates cognitive dysfunction and cerebral perfusion in heart failure

ML Alosco, MB Spitznagel, LH Sweet… - Pacing and clinical …, 2015 - Wiley Online Library
Background Heart failure (HF) increases risk for cognitive impairment in part due to the
negative effects of cardiac dysfunction on cerebral perfusion. Atrial fibrillation (AF), an …