ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets
Through harmonized procedures and by sharing site-specific brain metrics (for example,
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …
Smaller hippocampal volume in posttraumatic stress disorder: a multisite ENIGMA-PGC study: subcortical volumetry results from posttraumatic stress disorder …
Background Many studies report smaller hippocampal and amygdala volumes in
posttraumatic stress disorder (PTSD), but findings have not always been consistent. Here …
posttraumatic stress disorder (PTSD), but findings have not always been consistent. Here …
[HTML][HTML] Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA
A common limitation of neuroimaging studies is their small sample sizes. To overcome this
hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) …
hurdle, the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) …
Mega-analysis of gray matter volume in substance dependence: general and substance-specific regional effects
S Mackey, N Allgaier, B Chaarani… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Although lower brain volume has been routinely observed in individuals with
substance dependence compared with nondependent control subjects, the brain regions …
substance dependence compared with nondependent control subjects, the brain regions …
Cross-disorder analysis of brain structural abnormalities in six major psychiatric disorders: a secondary analysis of mega-and meta-analytical findings from the …
N Opel, J Goltermann, M Hermesdorf, K Berger… - Biological …, 2020 - Elsevier
Background Neuroimaging studies have consistently reported similar brain structural
abnormalities across different psychiatric disorders. Yet, the extent and regional distribution …
abnormalities across different psychiatric disorders. Yet, the extent and regional distribution …
Subcortical brain volume, regional cortical thickness, and cortical surface area across disorders: findings from the ENIGMA ADHD, ASD, and OCD working groups
PSW Boedhoe, D van Rooij… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD),
and obsessive-compulsive disorder (OCD) are common neurodevelopmental disorders that …
and obsessive-compulsive disorder (OCD) are common neurodevelopmental disorders that …
Cortical abnormalities associated with pediatric and adult obsessive-compulsive disorder: findings from the ENIGMA Obsessive-Compulsive Disorder Working Group
PSW Boedhoe, L Schmaal, Y Abe… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Brain imaging studies of structural abnormalities in OCD have yielded
inconsistent results, partly because of limited statistical power, clinical heterogeneity, and …
inconsistent results, partly because of limited statistical power, clinical heterogeneity, and …