There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Summary For a decade, The Cancer Genome Atlas (TCGA) program collected
clinicopathologic annotation data along with multi-platform molecular profiles of more than …

Importance Representative racial/ethnic participation in research, especially in clinical trials
that establish standards of care, is necessary to minimize disparities in outcomes and to …

In this article, the American Cancer Society provides the estimated number of new cancer
cases and deaths for blacks in the United States and the most recent data on cancer …

Intratumor heterogeneity (ITH) profoundly affects therapeutic responses and clinical
outcomes. However, the widespread methods for assessing ITH based on genomic …

Purpose Trop-2, expressed in most triple-negative breast cancers (TNBCs), may be a
potential target for antibody-drug conjugates. Sacituzumab govitecan, an antibody-drug …

Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …

Importance Variation in cancer incidence and outcome has well-documented correlations
with racial/ethnic identity. In the United States, the possible genetic and ancestral hereditary …

Triple negative breast cancer (TNBC) is a molecularly heterogeneous disease whose
incidence is disproportionately higher in African American (AA) women compared to …