Antimicrobial activities and mechanisms of extract and components of herbs in East Asia

J Liang, X Huang, G Ma - RSC advances, 2022 - pubs.rsc.org
Antibacterial drugs face increasing challenges due to drug resistance and adverse
reactions, which has created a pressing need for the discovery and development of novel …

Integrons in the development of antimicrobial resistance: critical review and perspectives

BA Bhat, RA Mir, H Qadri, R Dhiman… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors

S Sofi, U Mehraj, H Qayoom, S Aisha, A Almilaibary… - Medical Oncology, 2022 - Springer
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …

Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders

BA Bhat, A Almilaibary, RA Mir, BM Aljarallah… - Frontiers in …, 2022 - frontiersin.org
The current scientific community is facing a daunting challenge to unravel reliable natural
compounds with realistic potential to treat neurological disorders such as Alzheimer's …

Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya

WR Mir, BA Bhat, MA Rather, S Muzamil… - Scientific reports, 2022 - nature.com
Geranium wallichianum D. Don ex Sweet is a well-known medicinal plant in Kashmir
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …

Phytochemicals as antimicrobials: prospecting Himalayan medicinal plants as source of alternate medicine to combat antimicrobial resistance

MV Ashraf, S Pant, MAH Khan, AA Shah, S Siddiqui… - Pharmaceuticals, 2023 - mdpi.com
Among all available antimicrobials, antibiotics hold a prime position in the treatment of
infectious diseases. However, the emergence of antimicrobial resistance (AMR) has posed a …

Antimicrobial resistance: new insights and therapeutic implications

BA Sheikh, BA Bhat, MA Mir - Applied Microbiology and Biotechnology, 2022 - Springer
Antimicrobial resistance has not been a new phenomenon. Still, the number of resistant
organisms, the geographic areas affected by emerging drug resistance, and the magnitude …

Insights into the effects of hydroxycinnamic acid and its secondary metabolites as antioxidants for oxidative stress and plant growth under environmental stresses

S Khawula, A Gokul, LA Niekerk, G Basson… - Current Issues in …, 2023 - mdpi.com
Plant immobility renders plants constantly susceptible to various abiotic and biotic stresses.
Abiotic and biotic stresses are known to produce reactive oxygen species (ROS), which …

Manipulation and Exploitation Of Host Immune System by Pathogenic Mycobacterium Tuberculosis for its Advantage

MA Mir, B Mir, M Kumawat, M Alkhanani… - Future Microbiology, 2022 - Taylor & Francis
Mycobacterium tuberculosis (Mtb) can become a long-term infection by evading the host
immune response. Coevolution of Mtb with humans has resulted in its ability to hijack the …

Network pharmacology and experimental validation for deciphering the action mechanism of Fritillaria cirrhosa D. Don constituents in suppressing breast carcinoma

BA Bhat, W Rashid Mir, M Alkhanani… - Journal of …, 2023 - Taylor & Francis
Fritillaria cirrhosa D. Don is a well-known medicinal plant of Kashmir Himalaya. Traditionally,
it has been used to treat several diseases, including cancer. However, the molecular …