MSCs: delivery routes and engraftment, cell‐targeting strategies, and immune modulation
Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …
in clinical trials for multiple disease states. The differentiation, trophic, and …
Monocytes in coronary artery disease and atherosclerosis: where are we now?
Despite improvements in interventional and pharmacological therapy of atherosclerotic
disease, it is still the leading cause of death in the developed world. Hence, there is a need …
disease, it is still the leading cause of death in the developed world. Hence, there is a need …
Dual roles of graphene oxide to attenuate inflammation and elicit timely polarization of macrophage phenotypes for cardiac repair
Development of localized inflammatory environments by M1 macrophages in the cardiac
infarction region exacerbates heart failure after myocardial infarction (MI). Therefore, the …
infarction region exacerbates heart failure after myocardial infarction (MI). Therefore, the …
Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells
Objectives: The goal of this study was to conduct a direct head-to-head comparison of
different stem cell types in vitro for various assays of potency and in vivo for functional …
different stem cell types in vitro for various assays of potency and in vivo for functional …
Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis
V Jeevanantham, M Butler, A Saad, A Abdel-Latif… - Circulation, 2012 - Am Heart Assoc
Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …
[HTML][HTML] Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction
Recent studies suggest that the therapeutic effects of stem cell transplantation following
myocardial infarction (MI) are mediated by paracrine factors. One of the main goals in the …
myocardial infarction (MI) are mediated by paracrine factors. One of the main goals in the …
[HTML][HTML] Recent advances in the diagnosis and treatment of acute myocardial infarction
K Reddy, A Khaliq, RJ Henning - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
Abstract The Third Universal Definition of Myocardial Infarction (MI) requires cardiac
myocyte necrosis with an increase and/or a decrease in a patient's plasma of cardiac …
myocyte necrosis with an increase and/or a decrease in a patient's plasma of cardiac …
Cardioprotective microRNAs: Lessons from stem cell-derived exosomal microRNAs to treat cardiovascular disease
The stem cell-based therapy has emerged as a promising therapeutic strategy for treating
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However …
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However …
Cell therapy for cardiac repair—lessons from clinical trials
A Behfar, R Crespo-Diaz, A Terzic… - Nature Reviews …, 2014 - nature.com
The global impetus to identify curative therapies has been fuelled by the unmet needs of
patients in the context of a growing heart failure pandemic. To date, regeneration trials in …
patients in the context of a growing heart failure pandemic. To date, regeneration trials in …
Mesenchymal stem cell therapy: A promising cell‐based therapy for treatment of myocardial infarction
AES Shafei, MA Ali, HG Ghanem… - The journal of gene …, 2017 - Wiley Online Library
For decades, mesenchymal stem (MSCs) cells have been used for cardiovascular diseases
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …
as regenerative therapy. This review is an attempt to summarize the types of MSCs involved …