Objective To compare the risk for all cause and overdose mortality in people with opioid
dependence during and after substitution treatment with methadone or buprenorphine and …

Executive summary In September, 2015, the member states of the UN endorsed Sustainable
Development Goals (SDGs) for 2030, which aspire to human-rights-centred approaches to …

Background We used data from the Global Burden of Diseases, Injuries, and Risk Factors
Study 2010 (GBD 2010) to estimate the burden of disease attributable to mental and …

Summary Background The Millennium Declaration in 2000 brought special global attention
to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal …

Aims To estimate the effects of needle and syringe programmes (NSP) and opioid
substitution therapy (OST), alone or in combination, for preventing acquisition of hepatitis C …

During puberty, when young people are completing their education, transitioning into
employment, and forming longer-term intimate relationships, a shift in emotional regulation …

OBJECTIVE: To systematically review cohort studies of mortality among people who inject
drugs, examine mortality rates and causes of death in this group, and identify participant-and …

Background Opioid dependence is associated with low rates of treatment-seeking, poor
adherence to treatment, frequent relapse, and major societal consequences. We aimed to …

Drug use represents a significant burden to public health through disease, disability and
social problems, and policy makers are becoming increasingly interested in how to develop …

HIV can spread rapidly between people who inject drugs (through injections and sexual
transmission), and potentially the virus can pass to the wider community (by sexual …