[HTML][HTML] Mechanisms of allergen immunotherapy for inhaled allergens and predictive biomarkers

MH Shamji, SR Durham - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Immunological outcomes of allergen-specific immunotherapy in food allergy

AMM Schoos, D Bullens, BL Chawes, J Costa… - Frontiers in …, 2020 - frontiersin.org
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins.
Allergic reactions may present locally in different tissues such as skin, gastrointestinal and …

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper

MH Shamji, JH Kappen, M Akdis, E Jensen‐Jarolim… - Allergy, 2017 - Wiley Online Library
Background Allergen immunotherapy (AIT) is an effective treatment for allergic
rhinoconjunctivitis (AR) with or without asthma. It is important to note that due to the complex …

Oral immunotherapy for treatment of egg allergy in children

AW Burks, SM Jones, RA Wood… - … England Journal of …, 2012 - Mass Medical Soc
Background For egg allergy, dietary avoidance is the only currently approved treatment. We
evaluated oral immunotherapy using egg-white powder for the treatment of children with egg …

Immunological responses and biomarkers for allergen-specific immunotherapy against inhaled allergens

MH Shamji, JA Layhadi, H Sharif, M Penagos… - The Journal of Allergy …, 2021 - Elsevier
Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …

Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy

M Lao-Araya, E Steveling, GW Scadding… - Journal of Allergy and …, 2014 - jacionline.org
To the Editor: We report for the first time the effects of grass pollen subcutaneous
immunotherapy (SCIT) on the novel subset of innate lymphoid type 2 cells (ILC2s) in …

[HTML][HTML] Regulatory cytokine function in the respiratory tract

WJ Branchett, CM Lloyd - Mucosal immunology, 2019 - Elsevier
The respiratory tract is an important site of immune regulation; required to allow protective
immunity against pathogens, while minimizing tissue damage and avoiding aberrant …

Standardization of clinical outcomes used in allergen immunotherapy in allergic asthma: An EAACI position paper

J Kappen, Z Diamant, I Agache, M Bonini, J Bousquet… - Allergy, 2023 - Wiley Online Library
Introduction In allergic asthma patients, one of the more common phenotypes might benefit
from allergen immunotherapy (AIT) as add‐on intervention to pharmacological treatment …

[HTML][HTML] Allergy immunotherapy: the future of allergy treatment

JN Larsen, L Broge, H Jacobi - Drug discovery today, 2016 - Elsevier
Highlights•Allergy is increasing in prevalence and pharmacotherapy alone cannot control
the disease.•Allergy immunotherapy induces immunological tolerance and changes the …

Intralymphatic allergen-specific immunotherapy: an effective and safe alternative treatment route for pollen-induced allergic rhinitis

T Hylander, L Latif, U Petersson-Westin… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Allergen-specific immunotherapy is the only causative treatment of IgE-
mediated allergic disorders. The most common administration route is subcutaneous, which …