The past, present, and future of antibiotics
MA Cook, GD Wright - Science translational medicine, 2022 - science.org
Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …
diseases and enable vital therapies and procedures. However, despite this success, their …
Antimicrobial stewardship: fighting antimicrobial resistance and protecting global public health
MAA Majumder, S Rahman, D Cohall… - Infection and drug …, 2020 - Taylor & Francis
Antimicrobial resistance (AMR) is a serious threat to global public health. It increases
morbidity and mortality, and is associated with high economic costs due to its health care …
morbidity and mortality, and is associated with high economic costs due to its health care …
Antimicrobial resistance in ESKAPE pathogens
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …
Phage therapy in the postantibiotic era
FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …
number of infections are becoming harder or almost impossible to treat, carrying high …
[HTML][HTML] Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …
known as antibiotic resistance which is currently considered one of the principal threats to …
Drug combinations: a strategy to extend the life of antibiotics in the 21st century
Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …
[HTML][HTML] Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
The antibiotic resistome: a guide for the discovery of natural products as antimicrobial agents
The use of life-saving antibiotics has long been plagued by the ability of pathogenic bacteria
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …
A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens
M Song, Y Liu, X Huang, S Ding, Y Wang, J Shen… - Nature …, 2020 - nature.com
The rapid emergence and dissemination of multidrug-resistant (MDR) bacterial pathogens
pose a serious threat to global healthcare. One particular concern is the carbapenem …
pose a serious threat to global healthcare. One particular concern is the carbapenem …