Abnormal expression of mitochondrial ribosomal proteins and their encoding genes with cell apoptosis and diseases

G Huang, H Li, H Zhang - International journal of molecular sciences, 2020 - mdpi.com
Mammalian mitochondrial ribosomes translate 13 proteins encoded by mitochondrial genes,
all of which play roles in the mitochondrial respiratory chain. After a long period of …

[HTML][HTML] Connections for matters of the heart: network medicine in cardiovascular diseases

AR Sonawane, E Aikawa, M Aikawa - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Cardiovascular diseases (CVD) are diverse disorders affecting the heart and vasculature in
millions of people worldwide. Like other fields, CVD research has benefitted from the deluge …

Genomic analyses for selective signatures and genes involved in hot adaptation among indigenous chickens from different tropical climate regions

NY Xu, ZY Liu, QM Yang, PP Bian, M Li… - Frontiers in Genetics, 2022 - frontiersin.org
Climate change, especially weather extremes like extreme cold or extreme hot, is a major
challenge for global livestock. One of the animal breeding goals for sustainable livestock …

New insights into the role of mitochondrial metabolic dysregulation and immune infiltration in septic cardiomyopathy by integrated bioinformatics analysis and …

Y Li, J Yu, R Li, H Zhou, X Chang - Cellular & Molecular Biology Letters, 2024 - Springer
Background Septic cardiomyopathy (SCM), a common cardiovascular comorbidity of sepsis,
has emerged among the leading causes of death in patients with sepsis. SCM's …

Identification of immune-related hub genes and miRNA-mRNA pairs involved in immune infiltration in human septic cardiomyopathy by bioinformatics analysis

J Li, G Sun, H Ma, X Wu, C Li, P Ding, S Lu… - Frontiers in …, 2022 - frontiersin.org
Septic cardiomyopathy (SCM) is a serious complication caused by sepsis that will further
exacerbate the patient's prognosis. However, immune-related genes (IRGs) and their …

Exosome-encapsulated ncRNAs: Emerging yin and yang of tumor hallmarks

N Khan, MS Umar, M Haq, T Rauf, S Zubair… - Frontiers in …, 2022 - frontiersin.org
Tumorigenesis is a multifaceted process, where multiple physiological traits serving as
cancer's distinctive characteristics are acquired.“Hallmarks of cancer” is a set of cognitive …

[HTML][HTML] Identification and validation of immune-related biomarker gene and construction of ceRNA networks in septic cardiomyopathy

J Li, X Wu, C Li, G Sun, P Ding, Y Li, P Yang… - Frontiers in Cellular …, 2022 - frontiersin.org
Septic cardiomyopathy (SCM) is a cardiac dysfunction caused by severe sepsis, which
greatly increases the risk of heart failure and death, and its molecular mechanism is unclear …

Critical roles of ELVOL4 and IL-33 in the progression of obesity-related cardiomyopathy via integrated bioinformatics analysis

J Tao, Y Wang, L Li, J Zheng, S Liang - Frontiers in Physiology, 2020 - frontiersin.org
The molecular mechanisms underlying obesity-related cardiomyopathy (ORCM)
progression involve multiple signaling pathways, and the pharmacological treatment for …

Integrated genomic analysis defines molecular subgroups in dilated cardiomyopathy and identifies novel biomarkers based on machine learning methods

LF Ye, JY Weng, LD Wu - Frontiers in Genetics, 2023 - frontiersin.org
Aim: As the most common cardiomyopathy, dilated cardiomyopathy (DCM) often leads to
progressive heart failure and sudden cardiac death. This study was designed to investigate …

Screening of Key Genes for Triple-Negative Breast Cancer Based on a Differential Co-expression Method

J Yang, L Guo, Y Su, Y Zhang - 2022 41st Chinese Control …, 2022 - ieeexplore.ieee.org
The screening of key genes in triple-negative breast cancer is mainly studied in this paper. A
diagnostic model based on the differential co-expression network method DiffCoEx is …