Plaque rupture, usually of a precursor lesion known as a'vulnerable plaque'or'thin-cap
fibroatheroma', is the leading cause of thrombosis. Less-frequent aetiologies of coronary …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

Plaque microvascularization and increased endothelial permeability are key players in the
development of atherosclerosis, from the initial stages of plaque formation to the occurrence …

Today's concept of vulnerable plaque has evolved primarily from the early pioneering work
uncovering the pivotal role of plaque rupture and coronary thrombosis as the major cause of …

Objectives: The goal of this study was to identify histomorphologic characteristics of
atherosclerotic plaques and to determine the amenability of some of these components to be …

Background—Atherosclerotic plaques progress in a highly individual manner. The purposes
of the Prediction of Progression of Coronary Artery Disease and Clinical Outcome Using …

Identification of carotid artery atherosclerosis is conventionally based on measurements of
luminal stenosis and surface irregularities using in vivo imaging techniques including …

Observational studies of necrotic core progression identify intraplaque hemorrhage as a
critical factor in atherosclerotic plaque growth and destabilization. The rapid accumulation of …

Background—Atherosclerotic lesions are predominantly observed in curved arteries and
near side branches, where low or oscillatory shear stress patterns occur, suggesting a …

Background Intraplaque haemorrhage (IPH) drives atherosclerosis progression and is a key
imaging biomarker of unstable plaques. Non-invasive and sensitive monitoring of IPH is …