Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Liposomes and polymersomes: a comparative review towards cell mimicking

E Rideau, R Dimova, P Schwille, FR Wurm… - Chemical society …, 2018 - pubs.rsc.org
Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Biocatalytic cascades operating on macromolecular scaffolds and in confined environments

M Vázquez-González, C Wang, I Willner - Nature Catalysis, 2020 - nature.com
Biocatalytic cascades guide complex, efficient and selective intracellular transformations.
These unique features originate from the spatial organization of the biocatalysts in confined …

Endocytosis of coacervates into liposomes

T Lu, S Liese, L Schoenmakers, CA Weber… - Journal of the …, 2022 - ACS Publications
Recent studies have shown that the interactions between condensates and biological
membranes are of functional importance. Here, we study how the interaction between …

Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake

Q Jin, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Creating complex protocells and prototissues using simple DNA building blocks

N Arulkumaran, M Singer, S Howorka… - Nature …, 2023 - nature.com
Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal
frameworks. Recreating the complexity of cytoskeletal and exoskeletal fibers, with their …

A Biocatalytic Cascade in an Ultrastable Mesoporous Hydrogen‐Bonded Organic Framework for Point‐of‐Care Biosensing

Z Tang, X Li, L Tong, H Yang, J Wu… - Angewandte Chemie …, 2021 - Wiley Online Library
Herein, we report the first example of using mesoporous hydrogen‐bonded organic
frameworks (MHOFs) as the protecting scaffold to organize a biocatalytic cascade. The …