Autism spectrum disorder: focus on glutamatergic neurotransmission
M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors
R Bhandari, JK Paliwal, A Kuhad - … food intervention and therapy for autism …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons
Heterozygous loss-of-function mutations in SHANK2 are associated with autism spectrum
disorder (ASD). We generated cortical neurons from induced pluripotent stem cells derived …
disorder (ASD). We generated cortical neurons from induced pluripotent stem cells derived …
Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains
S Netser, A Meyer, H Magalnik, A Zylbertal… - Nature …, 2020 - nature.com
Mice and rats are widely used to explore mechanisms of mammalian social behavior in
health and disease, raising the question whether they actually differ in their social behavior …
health and disease, raising the question whether they actually differ in their social behavior …
Cerebellar and striatal implications in autism spectrum disorders: from clinical observations to animal models
M Thabault, V Turpin, A Maisterrena, M Jaber… - International Journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are complex conditions that stem from a combination of
genetic, epigenetic and environmental influences during early pre-and postnatal childhood …
genetic, epigenetic and environmental influences during early pre-and postnatal childhood …
Distinct mechanisms of over-representation of landmarks and rewards in the hippocampus
M Sato, K Mizuta, T Islam, M Kawano, Y Sekine… - Cell reports, 2020 - cell.com
In the hippocampus, locations associated with salient features are represented by a
disproportionately large number of neurons, but the cellular and molecular mechanisms …
disproportionately large number of neurons, but the cellular and molecular mechanisms …
Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings
Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …
Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …
Group 1 metabotropic glutamate receptors in neurological and psychiatric diseases: mechanisms and prospective
LD Su, N Wang, J Han, Y Shen - The Neuroscientist, 2022 - journals.sagepub.com
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors that are
activated by glutamate in the central nervous system (CNS). Basically, mGluRs contribute to …
activated by glutamate in the central nervous system (CNS). Basically, mGluRs contribute to …
LMT USV toolbox, a novel methodological approach to place mouse ultrasonic vocalizations in their behavioral contexts—a study in female and male C57BL/6J mice …
F de Chaumont, N Lemière, S Coqueran… - Frontiers in behavioral …, 2021 - frontiersin.org
Ultrasonic vocalizations (USVs) are used as a phenotypic marker in mouse models of
neuropsychiatric disorders. Nevertheless, current methodologies still require time …
neuropsychiatric disorders. Nevertheless, current methodologies still require time …