The emerging landscape of small nucleolar RNAs in cell biology
F Dupuis‐Sandoval, M Poirier… - Wiley interdisciplinary …, 2015 - Wiley Online Library
Small nucleolar RNAs (snoRNAs) are a large class of small noncoding RNAs present in all
eukaryotes sequenced thus far. As a family, they have been well characterized as playing a …
eukaryotes sequenced thus far. As a family, they have been well characterized as playing a …
Noncoding RNAs in eukaryotic ribosome biogenesis and function
DLJ Lafontaine - Nature structural & molecular biology, 2015 - nature.com
The ribosome, central to protein synthesis in all cells, is a complex multicomponent
assembly with rRNA at its functional core. During the process of ribosome biogenesis …
assembly with rRNA at its functional core. During the process of ribosome biogenesis …
Assembly and trafficking of box C/D and H/ACA snoRNPs
S Massenet, E Bertrand, C Verheggen - RNA biology, 2017 - Taylor & Francis
Box C/D and box H/ACA snoRNAs are abundant non-coding RNAs that localize in the
nucleolus and mostly function as guides for nucleotide modifications. While a large pool of …
nucleolus and mostly function as guides for nucleotide modifications. While a large pool of …
Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease
M McMahon, A Contreras… - Wiley Interdisciplinary …, 2015 - Wiley Online Library
A myriad of structurally and functionally diverse noncoding RNAs (ncRNAs) have recently
been implicated in numerous human diseases including cancer. Small nucleolar RNAs …
been implicated in numerous human diseases including cancer. Small nucleolar RNAs …
Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion‐positive prostate cancers
A Krohn, A Seidel, L Burkhardt… - The Journal of …, 2013 - Wiley Online Library
Deletion of 3p13 has been reported from about 20% of prostate cancers. The clinical
significance of this alteration and the tumour suppressor gene (s) driving the deletion remain …
significance of this alteration and the tumour suppressor gene (s) driving the deletion remain …
Unraveling the pathogenesis of Hoyeraal–Hreidarsson syndrome, a complex telomere biology disorder
Hoyeraal–Hreidarsson (HH) syndrome is a multisystem genetic disorder characterized by
very short telomeres and considered a clinically severe variant of dyskeratosis congenita …
very short telomeres and considered a clinically severe variant of dyskeratosis congenita …
[HTML][HTML] R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein
P Cloutier, C Poitras, M Durand, O Hekmat… - Nature …, 2017 - nature.com
Abstract The R2TP/Prefoldin-like (R2TP/PFDL) complex has emerged as a cochaperone
complex involved in the assembly of a number of critical protein complexes including …
complex involved in the assembly of a number of critical protein complexes including …
Biogenesis of telomerase ribonucleoproteins
ED Egan, K Collins - Rna, 2012 - rnajournal.cshlp.org
Telomerase adds simple-sequence repeats to the ends of linear chromosomes to counteract
the loss of end sequence inherent in conventional DNA replication. Catalytic activity for …
the loss of end sequence inherent in conventional DNA replication. Catalytic activity for …
RNA-guided isomerization of uridine to pseudouridine—pseudouridylation
YT Yu, UT Meier - RNA biology, 2014 - Taylor & Francis
Box H/ACA ribonucleoproteins (RNPs), each consisting of one unique guide RNA and 4
common core proteins, constitute a family of complex enzymes that catalyze, in an RNA …
common core proteins, constitute a family of complex enzymes that catalyze, in an RNA …
[HTML][HTML] Telomerase regulation from beginning to the end
DE MacNeil, HJ Bensoussan, C Autexier - Genes, 2016 - mdpi.com
The vast body of literature regarding human telomere maintenance is a true testament to the
importance of understanding telomere regulation in both normal and diseased states. In this …
importance of understanding telomere regulation in both normal and diseased states. In this …