New Antiplatelet Agents: Platelet GPIIb/llla Antagonists
BS Coller, K Anderson… - Thrombosis and …, 1995 - thieme-connect.com
The success of aspirin, and more recently ticlopidine, in treating and preventing ischemic
complications of thrombosis has stimulated the search for more potent agents (1, 2). The …
complications of thrombosis has stimulated the search for more potent agents (1, 2). The …
The utility of animal models in the preclinical study of interventions to prevent human coronary artery restenosis: analysis and recommendations
GJ Johnson, TR Griggs… - Thrombosis and …, 1999 - thieme-connect.com
Small animal models have several advantageous characteristics, but those used in
preclinical restenosis research have lacked efficacy in predicting the success of …
preclinical restenosis research have lacked efficacy in predicting the success of …
Development and validation of a prognostic risk score for major bleeding in patients undergoing percutaneous coronary intervention via the femoral approach
Aims Major bleeding after percutaneous coronary intervention (PCI) is an independent risk
factor for early and late mortality. We developed and validated a risk score predictive of …
factor for early and late mortality. We developed and validated a risk score predictive of …
Review of currently available GP IIb/IIIa inhibitors and their role in peripheral vascular interventions
PA Stangl, S Lewis - Seminars in interventional radiology, 2010 - thieme-connect.com
ABSTRACT The glycoprotein IIb/IIIa (GP IIb/IIIa) antagonists are the most recent additions to
the antiplatelet agents available to the interventional radiologist. The currently available GP …
the antiplatelet agents available to the interventional radiologist. The currently available GP …
[HTML][HTML] The stent decade: 1987 to 1997
SN Oesterle, R Whitbourn, PJ Fitzgerald, AC Yeung… - American heart …, 1998 - Elsevier
In January 1997, experts from the United States, Europe, and Japan gathered at Stanford
University to review their collective experience with intracoronary and noncoronary stenting …
University to review their collective experience with intracoronary and noncoronary stenting …
Different response to balloon angioplasty of carotid and coronary arteries: effects on acute platelet deposition and intimal thickening
JJ Badimon, AF Ortiz, B Meyer, A Mailhac, JT Fallon… - Atherosclerosis, 1998 - Elsevier
PTCA is a well-established intervention to reduce the severity of atherosclerotic coronary
stenosis. Its primary success rate is seriously handicapped by the high incidence of late …
stenosis. Its primary success rate is seriously handicapped by the high incidence of late …
Anti-human vWF monoclonal antibody, AJvW-2 Fab, inhibits repetitive coronary artery thrombosis without bleeding time prolongation in dogs
S Kageyama, H Yamamoto, H Nakazawa… - Thrombosis research, 2001 - Elsevier
The antithrombotic and antihaemostatic effects of the monoclonal antibody against human
vWF (AJvW-2 Fab) were investigated in comparison with those of the monoclonal antibody …
vWF (AJvW-2 Fab) were investigated in comparison with those of the monoclonal antibody …
Platelet GPIIb/IIIa binding characteristics of small molecule RGD mimetic: distinct binding profile for Roxifiban
A number of non‐peptide orally active RGD mimetic prodrug such as Orbofiban, Sibrafiban,
SR121566, Roxifiban and others entered into the clinical evaluation stage. Some of these …
SR121566, Roxifiban and others entered into the clinical evaluation stage. Some of these …
Comparison of the effect of different platelet GPIIb/IIIa antagonists on the dynamics of platelet/fibrin-mediated clot strength induced using thromboelastography
SA Mousa, MS Forsythe - Thrombosis research, 2001 - Elsevier
The effect of various platelet glycoprotein IIb/IIIa (GPIIb/IIIa) antagonists on the dynamics of
platelet–fibrin clot formation and strength induced by various stimuli was measured by …
platelet–fibrin clot formation and strength induced by various stimuli was measured by …
PAICA: a method for characterizing platelet-associated antibodies-its application to the study of idiopathic thrombocytopenic purpura and to the detection of platelet …
L Macchi, G Clofent-Sanchez, G Marit… - Thrombosis and …, 1996 - thieme-connect.com
In idiopathic thrombocytopenic purpura (ITP), autoantibodies reacting with antigens on the
platelet membrane bring about accelerated platelet destruction. We now report PAICA …
platelet membrane bring about accelerated platelet destruction. We now report PAICA …