Advances in lipid extraction methods—a review

RK Saini, P Prasad, X Shang, YS Keum - International Journal of …, 2021 - mdpi.com
Extraction of lipids from biological tissues is a crucial step in lipid analysis. The selection of
appropriate solvent is the most critical factor in the efficient extraction of lipids. A mixture of …

Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics

T Cajka, O Fiehn - Analytical chemistry, 2016 - ACS Publications
Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

R Laaksonen, K Ekroos, M Sysi-Aho… - European heart …, 2016 - academic.oup.com
Aims The aim was to study the prognostic value of plasma ceramides (Cer) as
cardiovascular death (CV death) markers in three independent coronary artery disease …

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma [S]

JA Bowden, A Heckert, CZ Ulmer, CM Jones… - Journal of lipid …, 2017 - ASBMB
As the lipidomics field continues to advance, self-evaluation within the community is critical.
Here, we performed an interlaboratory comparison exercise for lipidomics using Standard …

Sphingolipids and phospholipids in insulin resistance and related metabolic disorders

PJ Meikle, SA Summers - Nature Reviews Endocrinology, 2017 - nature.com
Obesity, insulin resistance, type 2 diabetes mellitus and cardiovascular disease form a
metabolic disease continuum that has seen a dramatic increase in prevalence in developed …

Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry

T Cajka, O Fiehn - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

Lipidomics: techniques, applications, and outcomes related to biomedical sciences

K Yang, X Han - Trends in biochemical sciences, 2016 - cell.com
Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

Plasmalogens and chronic inflammatory diseases

JC Bozelli Jr, S Azher, RM Epand - Frontiers in physiology, 2021 - frontiersin.org
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

HB Beyene, G Olshansky, AA T. Smith, C Giles… - PLoS …, 2020 - journals.plos.org
Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …

Lipidomics profiling and risk of cardiovascular disease in the prospective population-based Bruneck study

C Stegemann, R Pechlaner, P Willeit, SR Langley… - Circulation, 2014 - Am Heart Assoc
Background—The bulk of cardiovascular disease risk is not explained by traditional risk
factors. Recent advances in mass spectrometry allow the identification and quantification of …