Virus-like particles (VLPs) are multiprotein structures that mimic the organization and
conformation of authentic native viruses but lack the viral genome, potentially yielding safer …

In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …

The immature phenotype of human pluripotent stem cell derived cardiomyocytes (hPSC-
CMs) constrains their potential in cell therapy and drug testing. In this study, we report that …

The baculovirus‐insect cell expression system is widely used in producing recombinant
proteins. This review is focused on the use of this expression system in developing …

Insect cells (IC) and particularly lepidopteran cells are an attractive alternative to mammalian
cells for biomanufacturing. Insect cell culture, coupled with the lytic expression capacity of …

Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …

When a virus infects a host cell, it hijacks the biosynthetic capacity of the cell to produce
virus progeny, a process that may take less than an hour or more than a week. The overall …

Although microarray and expressed sequence tag (EST)-based approaches have been
used to profile gene expression during baculovirus infection, the response of host genes to …

Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …

Anchorage‐dependent cell cultures are used for the production of viruses, viral vectors, and
vaccines, as well as for various cell therapies and tissue engineering applications. Most of …