The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Rationale Love has long been referred to as an addiction in literature and poetry. Scientists
have often made comparisons between social attachment processes and drug addiction …

Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

Oxytocin neurons have a physiological role in food intake and energy balance. Central
administration of oxytocin is powerfully anorexigenic, reducing food intake and meal …

Pair bonds represent some of the strongest attachments we form as humans. These
relationships positively modulate health and well-being. Conversely, the loss of a spouse is …

Previous evidence in an animal model of drug self-administration and drug seeking showed
that acute oxytocin decreased methamphetamine (meth) seeking in male rats, suggesting …

Central oxytocin (OT) promotes feeding termination in response to homeostatic challenges,
such as excessive stomach distension, salt loading and toxicity. OT has also been proposed …

There is growing interest in the use of oxytocin (OT) as a potential treatment for alcohol and
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …

Drugs that act on the brain oxytocin (OXT) system may provide a much-needed treatment
breakthrough for substance-use disorders. Targeting the brain OXT system has the potential …

Background Evidence indicates that oxytocin, an endogenous peptide well known for its role
in social behaviors, childbirth, and lactation, is a promising addiction pharmacotherapy. We …