Polymeric micelles in cancer therapy: State of the art
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
Poloxamer: A versatile tri-block copolymer for biomedical applications
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
Cancer nanotechnology: a new revolution for cancer diagnosis and therapy
VK Chaturvedi, A Singh, VK Singh… - Current drug …, 2019 - ingentaconnect.com
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …
Recent advances in polymeric micelles for anti-cancer drug delivery
Block co-polymeric micelles receive increased attention due to their ability to load
therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …
therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …
Polymeric mixed micelles as nanomedicines: Achievements and perspectives
M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
Polymeric micelles as drug delivery vehicles
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …
Recent progress in biomedical applications of Pluronic (PF127): Pharmaceutical perspectives
Most of the administered anti-cancer drugs are hydrophobic in nature and are known to
have poor water solubility, short residence time, rapid clearance from the body and systemic …
have poor water solubility, short residence time, rapid clearance from the body and systemic …
The reversal of chemotherapy-induced multidrug resistance by nanomedicine for cancer therapy
S Liu, AR Khan, X Yang, B Dong, J Ji, G Zhai - Journal of Controlled …, 2021 - Elsevier
Multidrug resistance (MDR) of cancer is a persistent problem in chemotherapy. Scientists
have considered the overexpressed efflux transporters responsible for MDR and …
have considered the overexpressed efflux transporters responsible for MDR and …
A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance
Q He, Y Gao, L Zhang, Z Zhang, F Gao, X Ji, Y Li, J Shi - Biomaterials, 2011 - Elsevier
A type of pH-responsive nano multi-drug delivery systems (nano-MDDSs) with uniform
particle size (100±13 nm) and excellent monodispersity was developed by in situ co-self …
particle size (100±13 nm) and excellent monodispersity was developed by in situ co-self …
Nanotechnology applied to overcome tumor drug resistance
Z Gao, L Zhang, Y Sun - Journal of controlled release, 2012 - Elsevier
Emerging multidrug resistance (MDR) to chemotherapy is a major obstacle in successfully
treating malignant diseases. Nanotechnology provides an innovative and promising …
treating malignant diseases. Nanotechnology provides an innovative and promising …