[HTML][HTML] Insulin-like growth factor binding protein-3 (IGFBP-3): unraveling the role in mediating IGF-independent effects within the cell

S Varma Shrivastav, A Bhardwaj, KA Pathak… - Frontiers in cell and …, 2020 - frontiersin.org
Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), one of the six members of the
IGFBP family, is a key protein in the IGF pathway. IGFBP-3 can function in an IGF-dependent …

The mystery of nonclassical protein secretion: a current view on cargo proteins and potential export routes

W Nickel - European Journal of Biochemistry, 2003 - Wiley Online Library
Most of the examples of protein translocation across a membrane (such as the import of
classical secretory proteins into the endoplasmic reticulum, import of proteins into …

[HTML][HTML] Active caspase-1 is a regulator of unconventional protein secretion

M Keller, A Rüegg, S Werner, HD Beer - Cell, 2008 - cell.com
Mammalian cells export most proteins by the endoplasmic reticulum/Golgi-dependent
pathway. However, some proteins are secreted via unconventional, poorly understood …

[图书][B] Fungal cell wall: structure, synthesis, and assembly

J Ruiz-Herrera - 1991 - books.google.com
Fungal Cell Wall presents a comprehensive examination of the structure, synthesis, and
growth of the fungal cell wall and explores the reasons for the cell wall's importance to the …

[HTML][HTML] The Cu, Zn superoxide dismutase: not only a dismutase enzyme

P Mondola, S Damiano, A Sasso, M Santillo - Frontiers in physiology, 2016 - frontiersin.org
The Cu, Zn superoxide dismutase (SOD1) is an ubiquitary cytosolic dimeric carbohydrate
free molecule, belonging to a family of isoenzymes involved in the scavenger of superoxide …

Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells

W Nickel - Traffic, 2005 - Wiley Online Library
The vast majority of extracellular proteins are exported from mammalian cells by the
endoplasmic reticulum/Golgi‐dependent secretory pathway. For poorly understood reasons …

Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells

W Nickel, M Seedorf - Annual review of cell and developmental …, 2008 - annualreviews.org
The classical secretion of soluble proteins and transport of integral membrane proteins to
the cell surface require transit into and through the endoplasmic reticulum and the Golgi …

Comparing function and structure between entire proteomes

J Liu, B Rost - Protein Science, 2001 - Wiley Online Library
More than 30 organisms have been sequenced entirely. Here, we applied a variety of simple
bioinformatics tools to analyze 29 proteomes for representatives from all three kingdoms …

Extracellular roles for the molecular chaperone, hsp90

BK Eustace, DG Jay - Cell cycle, 2004 - Taylor & Francis
Heat shock proteins (hsps) are versatile molecular chaperones that are responsiblefor many
cellular functions including proper folding, oligomeric assembly, activation, and transport of …

Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2

C Zehe, A Engling, S Wegehingel… - Proceedings of the …, 2006 - National Acad Sciences
FGF-2 is an unconventionally secreted lectin that transmits proangiogenic signals through a
ternary complex with high-affinity FGF receptors and heparan sulfate proteoglycans …