A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …
Immunobiology of mesenchymal stem cells
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …
expanded in vitro. Although their true in situ properties and biological functions remain to be …
How mesenchymal stem cells interact with tissue immune responses
Mesenchymal stem cells (MSCs), also called multipotent mesenchymal stromal cells, exist in
almost all tissues and are a key cell source for tissue repair and regeneration. Under …
almost all tissues and are a key cell source for tissue repair and regeneration. Under …
Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions
M Di Trapani, G Bassi, M Midolo, A Gatti… - Scientific reports, 2016 - nature.com
Mesenchymal stromal cells (MSCs) are multipotent cells, immunomodulatory stem cells that
are currently used for regenerative medicine and treatment of a number of inflammatory …
are currently used for regenerative medicine and treatment of a number of inflammatory …
Mesenchymal stem cells: mechanisms of inflammation
In adults, human mesenchymal stem cells (hMSCs) are found in vivo at low frequency and
are defined by their capacity to differentiate into bone, cartilage, and adipose tissue …
are defined by their capacity to differentiate into bone, cartilage, and adipose tissue …
The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease …
J Galipeau - Cytotherapy, 2013 - Elsevier
The use of cryopreserved unmatched allogeneic mesenchymal stromal cells (MSCs) for
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
[HTML][HTML] The stem cell secretome and its role in brain repair
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models
L Bai, DP Lennon, AI Caplan, A DeChant… - Nature …, 2012 - nature.com
Mesenchymal stem cells (MSCs) have emerged as a potential therapy for a range of neural
insults. In animal models of multiple sclerosis, an autoimmune disease that targets …
insults. In animal models of multiple sclerosis, an autoimmune disease that targets …
Bone marrow stromal cells use TGF-β to suppress allergic responses in a mouse model of ragweed-induced asthma
Bone marrow stromal cells [BMSCs; also known as mesenchymal stem cells (MSCs)]
effectively suppress inflammatory responses in acute graft-versus-host disease in humans …
effectively suppress inflammatory responses in acute graft-versus-host disease in humans …
Immunogenicity of allogeneic mesenchymal stem cells
S Schu, M Nosov, L O'Flynn, G Shaw… - Journal of cellular …, 2012 - Wiley Online Library
Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low
levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion …
levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion …