Pathogenesis of distal symmetrical polyneuropathy in diabetes

S Smith, P Normahani, T Lane… - Life, 2022 - mdpi.com
Distal symmetrical polyneuropathy (DSPN) is a serious complication of diabetes associated
with significant disability and mortality. Although more than 50% of people with diabetes …

Changes in the central nervous system in diabetic neuropathy

Y Zang, D Jiang, X Zhuang, S Chen - Heliyon, 2023 - cell.com
One of the most common chronic complications arising from diabetes is diabetic peripheral
neuropathy. Depending on research statistics, approximately half of the people who have …

Structural imaging studies of patients with chronic pain: an anatomical likelihood estimate meta-analysis

AT Henn, B Larsen, L Frahm, A Xu, A Adebimpe… - Pain, 2023 - journals.lww.com
Neuroimaging is a powerful tool to investigate potential associations between chronic pain
and brain structure. However, the proliferation of studies across diverse chronic pain …

Early detection of diabetic peripheral neuropathy by fMRI: an evidence-based review

A Chitneni, A Rupp, J Ghorayeb, A Abd-Elsayed - Brain Sciences, 2022 - mdpi.com
With the significant rise in the prevalence of diabetes worldwide, diabetic peripheral
neuropathy (DPN) remains the most common complication among type 1 and 2 diabetics …

Altered gray matter volume, functional connectivity, and degree centrality in early-onset type 2 diabetes mellitus

Y Feng, Y Li, X Tan, Y Liang, X Ma, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Background: Structural and functional brain alterations that underlie cognitive decline have
been observed in elderly adults with type 2 diabetes mellitus (T2DM); however, whether …

Novel insights into the nervous system affected by prolonged hyperglycemia

K Zglejc-Waszak, K Mukherjee, A Korytko… - Journal of Molecular …, 2023 - Springer
Multiple molecular pathways including the receptor for advanced glycation end-products-
diaphanous related formin 1 (RAGE-Diaph1) signaling are known to play a role in diabetic …

Structural and functional brain signatures of endurance runners

L Cao, Y Zhang, R Huang, L Li, F Xia, L Zou… - Brain Structure and …, 2021 - Springer
Although endurance running (ER) seems to be a simple repetitive exercise, good ER
performance also requires and relies on multiple cognitive and motor control processes …

Structural brain alterations in key somatosensory and nociceptive regions in diabetic peripheral neuropathy

D Selvarajah, G Sloan, K Teh, ID Wilkinson… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Despite increasing evidence demonstrating structural and functional alterations
within the central nervous system in diabetic peripheral neuropathy (DPN), the …

Detecting type 2 diabetes mellitus cognitive impairment using whole-brain functional connectivity

J Wu, Y Fang, X Tan, S Kang, X Yue, Y Rao… - Scientific Reports, 2023 - nature.com
Type 2 diabetes mellitus (T2DM) is closely linked to cognitive decline and alterations in
brain structure and function. Resting-state functional magnetic resonance imaging (rs-fMRI) …

Surface-based falff: a potential novel biomarker for prediction of radiation encephalopathy in patients with nasopharyngeal carcinoma

Y Zhang, Y Kang, J Zeng, L Li, J Gao, L Liu… - Frontiers in …, 2021 - frontiersin.org
Radiation encephalopathy (RE) is an important potential complication in patients with
nasopharyngeal carcinoma (NPC) who undergo radiotherapy (RT) that can affect the quality …