Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Background: Animal spinal cord injury (SCI) models have proved invaluable in better
understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of …

Dexmedetomidine (DEX), a highly specific α2‑adrenergic agonist, which exhibits
anaesthetic‑sparing, analgesia and sympatholytic properties. DEX modulates gene …

Distraction spinal cord injuries (DSCIs) often occur as the neurological complication of
distraction forces following the implantation of internal fixation devices during scoliosis …

Abstract Background Dexmedetomidine (Dex) can improve neuronal viability and protect the
spinal cord from ischemia–reperfusion (I/R) injury, but the underlying mechanisms are not …

Background Neuroinflammation and cellular apoptosis caused by spinal cord
ischemia/reperfusion (I/R) injury result in neurological dysfunction. MicroRNAs (miRs) have …

It has been shown that animal spinal cord compression (using methods such as clips,
balloons, spinal cord strapping, or calibrated forceps) mimics the persistent spinal canal …

The aim of this experimental study was to investigate the possible protective effects of
dantrolene on traumatic spinal cord injury (SCI). Twenty-four New Zealand rabbits were …

Microglial cell activation after spinal cord ischemia-reperfusion injury (SCIRI) commonly
causes the secondary nerve motion function injury. This study aims to study the mechanism …

Dexmedetomidine (DEX) is an α2‐adrenergic agonist. It decreases the levels of
norepinephrine release, resulting in a reduction of postsynaptic adrenergic activity. In the …