Using clusterProfiler to characterize multiomics data

S Xu, E Hu, Y Cai, Z Xie, X Luo, L Zhan, W Tang… - Nature …, 2024 - nature.com
With the advent of multiomics, software capable of multidimensional enrichment analysis
has become increasingly crucial for uncovering gene set variations in biological processes …

[HTML][HTML] Severe COVID-19 infection and pediatric comorbidities: a systematic review and meta-analysis

BK Tsankov, JM Allaire, MA Irvine, AA Lopez… - International Journal of …, 2021 - Elsevier
Objective There is limited information on the severity of COVID-19 infection in children with
comorbidities. We investigated the effects of pediatric comorbidities on COVID-19 severity by …

CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2015–2019

QT Ostrom, M Price, C Neff, G Cioffi, KA Waite… - Neuro …, 2022 - academic.oup.com
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control and Prevention and the National Cancer Institute, is the …

[HTML][HTML] The manifold costs of being a non-native English speaker in science

T Amano, V Ramírez-Castañeda… - PLoS …, 2023 - journals.plos.org
The use of English as the common language of science represents a major impediment to
maximising the contribution of non-native English speakers to science. Yet few studies have …

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

C Abbosh, AM Frankell, T Harrison, J Kisistok… - Nature, 2023 - nature.com
Circulating tumour DNA (ctDNA) can be used to detect and profile residual tumour cells
persisting after curative intent therapy. The study of large patient cohorts incorporating …

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

C Cervia-Hasler, SC Brüningk, T Hoch, B Fan, G Muzio… - Science, 2024 - science.org
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …

Taurine deficiency as a driver of aging

P Singh, K Gollapalli, S Mangiola, D Schranner… - Science, 2023 - science.org
Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …

[图书][B] Doing meta-analysis with R: A hands-on guide

M Harrer, P Cuijpers, T Furukawa, D Ebert - 2021 - taylorfrancis.com
Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on
how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered …

Can language models learn from explanations in context?

AK Lampinen, I Dasgupta, SCY Chan… - arXiv preprint arXiv …, 2022 - arxiv.org
Language Models (LMs) can perform new tasks by adapting to a few in-context examples.
For humans, explanations that connect examples to task principles can improve learning …

Vaccination induces HIV broadly neutralizing antibody precursors in humans

DJ Leggat, KW Cohen, JR Willis, WJ Fulp, AC Decamp… - Science, 2022 - science.org
Broadly neutralizing antibodies (bnAbs) can protect against HIV infection but have not been
induced by human vaccination. A key barrier to bnAb induction is vaccine priming of rare …