Iron is indispensable for normal body functions across species because of its critical roles in
red blood cell function and many essential proteins and enzymes required for numerous …

Hypoxia-inducible factor (HIF) plays a crucial role in the response to hypoxia at the cellular,
tissue, and organism level. New agents under development to pharmacologically …

In this study, a series of di-O-caffeoylquinic acids (di-COQs) were systematically investigated
for their antioxidant and cytoprotective effects towards• OH-damaged bone marrow-derived …

Accumulating evidence indicates that oxidative stress plays a role in the pathophysiology of
chronic kidney disease (CKD) and its progression; during renal replacement therapy …

Background End-stage renal disease (ESRD) causes premature ageing of the immune
system. However, it is not known whether hemodialysis (HD) and peritoneal dialysis (PD) …

Telomeres are dynamic DNA nucleoprotein structures located at the end of chromosomes
where they maintain genomic stability. Due to the end replication problem, telomeres …

Aim: Both oxidative stress and inflammation are involved in the pathogenesis of
cardiovascular disease (CVD). The serum level of derivatives of reactive oxygen metabolites …

End-stage renal disease (ESRD) patients exhibit clinical features of premature ageing,
including frailty, cardiovascular disease, and muscle wasting. Accelerated ageing also …

Vitamin C, an excellent reducing agent, aids in increasing absorbable ferrous iron in iron
deficiency anemia. As an efficient antioxidant, it is still unknown whether vitamin C exerts …

Background Excess iron levels can induce oxidative stress and could therefore affect
telomere attrition. However, little is known about the impact of body iron status on telomere …