Advantages and limitations of microarray technology in human cancer
G Russo, C Zegar, A Giordano - Oncogene, 2003 - nature.com
Cancer is a highly variable disease with multiple heterogeneous genetic and epigenetic
changes. Functional studies are essential to understanding the complexity and …
changes. Functional studies are essential to understanding the complexity and …
Nutrigenomics: from molecular nutrition to prevention of disease
Until recently, nutrition research concentrated on nutrient deficiencies and impairment of
health. The advent of genomics—interpreted broadly as a suite of high throughput …
health. The advent of genomics—interpreted broadly as a suite of high throughput …
Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers
J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …
Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant
T Fehm, A Sagalowsky, E Clifford, P Beitsch… - Clinical cancer …, 2002 - AACR
Purpose: Numerous studies of circulating epithelial cells (CECs) have been described in
cancer patients, and genetic abnormalities have been well documented. However, with one …
cancer patients, and genetic abnormalities have been well documented. However, with one …
[HTML][HTML] Assessing the human immune system through blood transcriptomics
Blood is the pipeline of the immune system. Assessing changes in transcript abundance in
blood on a genome-wide scale affords a comprehensive view of the status of the immune …
blood on a genome-wide scale affords a comprehensive view of the status of the immune …
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia
Microarray techniques hold great promise for identifying risk factors for schizophrenia (SZ)
but have not yet generated widely reproducible results due to methodological differences …
but have not yet generated widely reproducible results due to methodological differences …
Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2
G Regl, M Kasper, H Schnidar, T Eichberger, GW Neill… - Cancer Research, 2004 - AACR
Aberrant activation of the Hedgehog (HH)/GLI signaling pathway has been implicated in the
development of basal cell carcinoma (BCC). The zinc finger transcription factors GLI1 and …
development of basal cell carcinoma (BCC). The zinc finger transcription factors GLI1 and …
[HTML][HTML] Viral inhibition of the IFN-induced JAK/STAT signalling pathway: development of live attenuated vaccines by mutation of viral-encoded IFN-antagonists
SB Fleming - Vaccines, 2016 - mdpi.com
The interferon (IFN) induced anti-viral response is amongst the earliest and most potent of
the innate responses to fight viral infection. The induction of the Janus kinase/signal …
the innate responses to fight viral infection. The induction of the Janus kinase/signal …
Circulating tumor cells, disease progression, and survival in metastatic breast cancer
M Cristofanilli - Seminars in oncology, 2006 - Elsevier
Metastatic breast cancer (MBC) is considered incurable; therefore, palliative treatment is the
only option. The biologic heterogeneity of the disease is reflected in its somewhat …
only option. The biologic heterogeneity of the disease is reflected in its somewhat …
Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma
G Regl, GW Neill, T Eichberger, M Kasper, MS Ikram… - Oncogene, 2002 - nature.com
Transgenic mouse models have provided evidence that activation of the zinc-finger
transcription factor GLI1 by Hedgehog (Hh)-signalling is a key step in the initiation of the …
transcription factor GLI1 by Hedgehog (Hh)-signalling is a key step in the initiation of the …