What is known and objective Genetic polymorphism is one of the most important factors
responsible for interindividual and interethnic variability in drug response. Studies in major …

El cáncer de seno es un grupo de enfermedades con gran impacto a nivel mundial dado
que es una de las patologías con mayor prevalencia en mujeres y el cáncer con mayor tasa …

Background: Data on the frequency of pharmacogenetic polymorphisms in the Croatian
population are limited. We determined and analyzed frequencies for the most important …

Single nucleotide and structural variants of CYP2D6 gene in... : Medicine Single nucleotide
and structural variants of CYP2D6 gene in Kinh Vietnamese population : Medicine Log in or …

Introduction CYP2C19 plays a major role in the metabolism of various drugs. The most
common genetic variants were the CYP2C19* 2 and* 3 alleles (rs4244285 and rs4986893 …

Single-nucleotide polymorphisms (SNPs) among drug-metabolizing enzymes and
transporters (DMETs) influence the pharmacokinetic profile of drugs and exhibit intra-and …

Background Marked differences among genotype frequencies (Caucasians, Asians, and
Africans) have been observed in cytochrome P450 (CYP) genes. Data on the frequency of …

The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications.
Unconjugated hyperbilirubinemia, commonly presented as Gilbert syndrome (GS), is a result …

Non-pharmacological treatment including diet, body weight reduction, smoking cessation
and physical activity, is very important part of hypertension treatment. The objective of this …

Sažetak Cytochrome P450 genetic polymorphisms are responsible for individual variations
in drug metabolism and drug-drug interactions. They are very important for …