Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges
Topical preexposure prophylaxis interrupts HIV transmission at the site of mucosal
exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse transcriptase …
exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse transcriptase …
Microbicides: still a long road to success
C Vanpouille, A Arakelyan, L Margolis - Trends in microbiology, 2012 - cell.com
The development of efficient microbicides, the topically applied compounds that protect
uninfected individuals from acquiring HIV-1, is a promising strategy to contain HIV-1 …
uninfected individuals from acquiring HIV-1, is a promising strategy to contain HIV-1 …
[HTML][HTML] Chitosan-poly (ethylene oxide) nanofibrous mat as a vaginal platform for tenofovir disoproxyl fumarate–The effect of vaginal pH on drug carrier performance
E Szymańska, M Wojasiński, J Dąbrowska… - International Journal of …, 2022 - Elsevier
In the present work, a solution blow spun nanofibrous mat comprised of chitosan (CS) and
poly (ethylene oxide)(PEO) was obtained as vaginal platform for tenofovir disoproxil …
poly (ethylene oxide)(PEO) was obtained as vaginal platform for tenofovir disoproxil …
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
C Tintori, G Iovenitti, ER Ceresola, R Ferrarese… - PLoS …, 2018 - journals.plos.org
Although highly active antiretroviral therapies (HAART) remarkably increased life
expectancy of HIV positive people, the rate of novel HIV-1 infections worldwide still …
expectancy of HIV positive people, the rate of novel HIV-1 infections worldwide still …
Layer-by-layer engineered microbicide drug delivery system targeting HIV-1 gp120: physicochemical and biological properties
FS Coulibaly, MJM Ezoulin, SS Purohit… - Molecular …, 2017 - ACS Publications
The purpose of this study was to engineer a model anti-HIV microbicide (tenofovir) drug
delivery system targeting HIV-1 envelope glycoprotein gp120 (HIV-1 g120) for the …
delivery system targeting HIV-1 envelope glycoprotein gp120 (HIV-1 g120) for the …
Development of methods for cross-sectional HIV incidence estimation in a large, community randomized trial
O Laeyendecker, M Kulich, D Donnell, A Komárek… - PloS one, 2013 - journals.plos.org
Background Accurate methods of HIV incidence determination are critically needed to
monitor the epidemic and determine the population level impact of prevention trials. One …
monitor the epidemic and determine the population level impact of prevention trials. One …
Antibody maturation in women who acquire HIV infection while using antiretroviral preexposure prophylaxis
The CAPRISA 004 preexposure prophylaxis (PrEP) randomized trial demonstrated that
women who used a vaginal gel containing the antiretroviral drug tenofovir (TFV) had a 39 …
women who used a vaginal gel containing the antiretroviral drug tenofovir (TFV) had a 39 …
Replication capacity of viruses from acute infection drives HIV-1 disease progression
P Selhorst, C Combrinck, N Ndabambi… - Journal of …, 2017 - Am Soc Microbiol
The viral genotype has been shown to play an important role in HIV pathogenesis following
transmission. However, the viral phenotypic properties that contribute to disease …
transmission. However, the viral phenotypic properties that contribute to disease …
An intravaginal ring for the simultaneous delivery of an HIV-1 maturation inhibitor and reverse-transcriptase inhibitor for prophylaxis of HIV transmission
SR Ugaonkar, JT Clark, LB English, TJ Johnson… - Journal of …, 2015 - Elsevier
ABSTRACT Nucleocapsid 7 (NCp7) inhibitors have been investigated extensively for their
role in impeding the function of HIV-1 replication machinery and their ability to directly …
role in impeding the function of HIV-1 replication machinery and their ability to directly …
[PDF][PDF] Chitosan-poly (ethylene oxide) nanofibrous mat as a vaginal platform for tenofovir disoproxyl fumarate–The effect of vaginal pH on drug carrier performance
E Szymanska, M Wojasinski, J Dąbrowska… - … Journal of Biological …, 2022 - repo.pw.edu.pl
In the present work, a solution blow spun nanofibrous mat comprised of chitosan (CS) and
poly (ethylene oxide)(PEO) was obtained as vaginal platform for tenofovir disoproxil …
poly (ethylene oxide)(PEO) was obtained as vaginal platform for tenofovir disoproxil …