Several neurodegenerative disorders involve impaired neurotransmission, and
glutamatergic neurotransmission sets a prototypical example. Glutamate is a predominant …

Endogenously synthesized trehalose is a stress protectant in Escherichia coli. Externally
supplied trehalose does not serve as a stress protectant, but it can be utilized as the sole …

Regulation of chromosomally determined nutrient cation and anion uptake systems shows
important similarities to regulation of plasmid-determined toxic ion resistance systems that …

Methylglyoxal is a toxic electrophile. In Escherichia coli cells, the principal route of
methylglyoxal production is from dihydroxyacetone phosphate by the action of methylglyoxal …

A list of currently identified gene products of Escherichia coli is given, together with a
bibliography that provides pointers to the literature on each gene product. A scheme to …

Glutathione metabolism and its role in vital functions of bacterial cells are considered, as
well as common features and differences between the functions of glutathione in prokaryotic …

The transmissible locus of stress tolerance (tLST) is found mainly in beta-and gamma-
Proteobacteria and confers tolerance to elevated temperature, pressure, and chlorine. This …

The glyoxalase I gene (gloA) of Escherichia coli has been cloned and used to create a null
mutant. Cells overexpressing glyoxalase I exhibit enhanced tolerance of methylglyoxal (MG) …

The regulation of cation content is critical for cell growth. However, the molecular
mechanisms that gate the systems that control K+ movements remain unclear. KTN is a …

Methylglyoxal (MG) is a toxic by‐product of glycolysis that damages DNA and proteins
ultimately leading to cell death. Protection from MG is often conferred by a glutathione …