Recent findings in epigenetics shed new light on the regulation of gene expression in the
central nervous system (CNS) during stress. The most frequently studied epigenetic …

An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …

Many studies have consistently demonstrated an epigenetic link between environmental
stimuli and physiological as well as cognitive responses. Epigenetic mechanisms represent …

Background Alterations in gene expression in the suicide brain have been reported and for
several genes DNA methylation as an epigenetic regulator is thought to play a role. rRNA …

Phenotypic diversity is shaped by both genetic and epigenetic mechanisms that program
tissue specific patterns of gene expression. Cells, including neurons, undergo massive …

Depression is a common and disabling psychiatric disorder with a complex etiology, which
includes predisposing risk genes and environmental stressors. Variation in the Catechol-O …

Offspring of persons exposed to childhood abuse are at higher risk of neurodevelopmental
and physical health disparities across the life course. Animal experiments have indicated …

Background: Impaired stress resilience and a dysfunctional hypothalamic-pituitary-adrenal
(HPA) axis are suggested to play key roles in the pathophysiology of illness progression in …

Psychiatric diseases place a tremendous burden on affected individuals, their caregivers,
and the health care system. Although evidence exists for a strong inherited component to …

BackgroundA growing number of studies suggest a link between timing of menarche and
risk of depressive symptoms in adolescence, but few have prospectively examined the …