Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease

X Wang, W Huang, L Su, Y Xing, F Jessen… - Molecular …, 2020 - Springer
Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the
Alzheimer's disease (AD) continuum. Investigating populations with SCD is important for …

A metabolism‐functional connectome sparse coupling method to reveal imaging markers for Alzheimer's disease based on simultaneous PET/MRI scans

L Wang, H Xu, M Wang, M Brendel… - Human brain …, 2023 - Wiley Online Library
Abnormal glucose metabolism and hemodynamic changes in the brain are closely related to
cognitive function, providing complementary information from distinct biochemical and …

Functional connectivity dynamics altered of the resting brain in subjective cognitive decline

YC Wei, YC Kung, WY Huang, C Lin… - Frontiers in Aging …, 2022 - frontiersin.org
Background Subjective cognitive decline (SCD) appears in the preclinical stage of the
Alzheimer's disease continuum. In this stage, dynamic features are more sensitive than static …

Static and dynamic functional connectivity variability of the anterior-posterior hippocampus with subjective cognitive decline

Q Wang, B Chen, X Zhong, L Hou, M Zhang… - Alzheimer's Research & …, 2022 - Springer
Background Subjective cognitive decline (SCD) is a putative Alzheimer's disease (AD)
precursor without objective neuropsychological deficits. The hippocampus plays an …

Dynamics and concordance abnormalities among indices of intrinsic brain activity in individuals with subjective cognitive decline: a temporal dynamics resting-state …

Y Yang, X Zha, X Zhang, J Ke, S Hu, X Wang… - Frontiers in Aging …, 2021 - frontiersin.org
Individuals with subjective cognitive decline (SCD) are more likely to develop into Alzheimer
disease (AD) in the future. Resting-state functional magnetic resonance imaging (rs-fMRI) …

Voxelwise meta-analysis of gray matter abnormalities in mild cognitive impairment and subjective cognitive decline using activation likelihood estimation

S Chen, W Xu, C Xue, G Hu, W Ma… - Journal of …, 2020 - content.iospress.com
Background: Voxel-based morphometry studies have not yielded consistent results among
patients with mild cognitive impairment (MCI) and subjective cognitive decline (SCD) …

Identification of earlier biomarkers for Alzheimer's disease: a multimodal neuroimaging study of individuals with subjective cognitive decline

AF Parker, CM Smart, V Scarapicchia… - Journal of …, 2020 - content.iospress.com
Background: Individuals with subjective cognitive decline (SCD) are thought to be the
earliest along the cognitive continuum between healthy aging and Alzheimer's disease (AD) …

Abnormal regional and global connectivity measures in subjective cognitive decline depending on cerebral amyloid status

S Li, M Daamen, L Scheef, FC Gaertner… - Journal of …, 2021 - content.iospress.com
Background: Amyloid-accumulation was found to alter precuneus-based functional
connectivity (FC) in mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia …

Altered pattern analysis and identification of subjective cognitive decline based on morphological brain network

X Xu, P Chen, Y Xiang, Z Xie, Q Yu, X Zhou… - Frontiers in Aging …, 2022 - frontiersin.org
Subjective cognitive decline (SCD) is considered the first stage of Alzheimer's disease (AD).
Accurate diagnosis and the exploration of the pathological mechanism of SCD are extremely …

Connectivity and variability of related cognitive subregions lead to different stages of progression toward Alzheimer's disease

J Sheng, B Wang, Q Zhang, M Yu - Heliyon, 2022 - cell.com
Single modality MRI data is not enough to depict and discern the cause of the underlying
brain pathology of Alzheimer's disease (AD). Most existing studies do not perform well with …