Current methods for hyperpolarized [1‐13C]pyruvate MRI human studies

PEZ Larson, JML Bernard, JA Bankson… - Magnetic resonance …, 2024 - Wiley Online Library
Abstract MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can
measure processes such as localized metabolism that is altered in numerous cancers, liver …

[HTML][HTML] Hyperpolarized [2–13C] pyruvate MR molecular imaging with whole brain coverage

BT Chung, Y Kim, JW Gordon, HY Chen, AW Autry… - NeuroImage, 2023 - Elsevier
Abstract Hyperpolarized (HP) 13 C Magnetic Resonance Imaging (MRI) was applied for the
first time to image and quantify the uptake and metabolism of [2–13 C] pyruvate in the …

[HTML][HTML] Hyperpolarized Xenon-129 Chemical Exchange Saturation Transfer (HyperCEST) Molecular Imaging: Achievements and Future Challenges

V Batarchuk, Y Shepelytskyi, V Grynko… - International Journal of …, 2024 - mdpi.com
Molecular magnetic resonance imaging (MRI) is an emerging field that is set to revolutionize
our perspective of disease diagnosis, treatment efficacy monitoring, and precision medicine …

[HTML][HTML] 129Xe MRI ventilation defects in asthma: what is the upper limit of normal and minimal clinically important difference?

MJ McIntosh, A Biancaniello, HK Kooner, A Bhalla… - Academic …, 2023 - Elsevier
Rationale and Objectives The minimal clinically important difference (MCID) and upper limit
of normal (ULN) for MRI ventilation defect percent (VDP) were previously reported for …

Analytical corrections for B1‐inhomogeneity and signal decay in multi‐slice 2D spiral hyperpolarized 129Xe MRI using keyhole reconstruction

JW Plummer, R Hussain, AS Bdaiwi… - Magnetic …, 2024 - Wiley Online Library
Purpose Hyperpolarized xenon MRI suffers from heterogeneous coil bias and magnetization
decay that obscure pulmonary abnormalities. Non‐physiological signal variability can be …

B1 and magnetization decay correction for hyperpolarized 129Xe lung imaging using sequential 2D spiral acquisitions

AS Bdaiwi, ML Costa, JW Plummer… - Magnetic …, 2023 - Wiley Online Library
Purpose To mitigate signal variations caused by inhomogeneous RF and magnetization
decay in hyperpolarized 129Xe ventilation images using flip‐angle maps generated from …

[HTML][HTML] Functional gas exchange measures on 129Xe MRI and spectroscopy are associated with age, sex, and BMI in healthy subjects

D Mummy, S Zhang, A Bechtel, J Lu… - Frontiers in …, 2024 - frontiersin.org
Introduction Hyperpolarized 129Xe MRI and spectroscopy is a rapidly growing technique for
assessing lung function, with applications in a wide range of obstructive, restrictive, and …

Advances in NMR spectroscopy of small molecules in solution

P Nolis - 2023 - books.rsc.org
This book chapter covers relevant articles published in peer-reviewed journals in 2022 in
the field of NMR spectroscopy of small molecules in solution. Articles that appeared in 2022 …

Eosinophilic Asthma Response to Therapy: 129Xe Magnetic Resonance Imaging and Computed Tomography

MJ McIntosh - 2023 - search.proquest.com
Novel biologic therapies, such as anti-interleukin-5 receptor α (anti-IL-5Rα) or benralizumab,
have been developed to treat patients with severe eosinophilic asthma who experience …

Hyperpolarisation techniques

A Equbal, RE Mewis - 2023 - books.rsc.org
This chapter focuses on the literature published in 2022, covering hyperpolarisation
techniques associated with NMR. The literature reviewed relates to the hyperpolarisation …