A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

S Fuloria, J Mehta, A Chandel, M Sekar… - Frontiers in …, 2022 - frontiersin.org
Curcuma longa Linn.(C. longa), popularly known as turmeric, belongs to the Zingiberaceae
family and has a long historical background of having healing properties against many …

SIRT1 activation by natural phytochemicals: an overview

C Iside, M Scafuro, A Nebbioso, L Altucci - Frontiers in pharmacology, 2020 - frontiersin.org
Sirtuins are class III histone deacetylases, whose enzymatic activity is dependent on NAD+
as a cofactor. Sirtuins are reported to modulate numerous activities by controlling gene …

Curcumin and type 2 diabetes mellitus: prevention and treatment

F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update

S Ghosh, S Banerjee, PC Sil - Food and Chemical Toxicology, 2015 - Elsevier
The concept of using phytochemicals has ushered in a new revolution in pharmaceuticals.
Naturally occurring polyphenols (like curcumin, morin, resveratrol, etc.) have gained …

Biochemistry, safety, pharmacological activities, and clinical applications of turmeric: a mechanistic review

RS Ahmad, MB Hussain, MT Sultan… - Evidence‐Based …, 2020 - Wiley Online Library
Turmeric (Curcuma longa L.) is a popular natural drug, traditionally used for the treatment of
a wide range of diseases. Its root, as its most popular part used for medicinal purposes …

Diabetes and plant‐derived natural products: From ethnopharmacological approaches to their potential for modern drug discovery and development

AK Jugran, S Rawat, HP Devkota, ID Bhatt… - Phytotherapy …, 2021 - Wiley Online Library
Diabetes is a disease of serious concern faced by the health care industry today. Primary
diabetes mellitus and its complications are still costly to manage with modern drugs …

The potential and action mechanism of polyphenols in the treatment of liver diseases

S Li, HY Tan, N Wang, F Cheung… - … medicine and cellular …, 2018 - Wiley Online Library
Liver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …

Turmeric and its bioactive constituents trigger cell signaling mechanisms that protect against diabetes and cardiovascular diseases

HA Zhang, DD Kitts - Molecular and cellular biochemistry, 2021 - Springer
Turmeric, the rhizome of Curcuma longa plant belonging to the ginger family Zingiberaceae,
has a history in Ayurvedic and traditional Chinese medicine for treatment of chronic …

[HTML][HTML] Pharmacological mechanisms and clinical applications of curcumin: update

M Hao, Y Chu, J Lei, Z Yao, P Wang, Z Chen… - Aging and …, 2023 - ncbi.nlm.nih.gov
Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric
(Curcuma longa L.), has attracted great interest in the last ten years due to its multiple …

Targeting NF-κB signaling pathway in cancer by dietary polyphenols

H Khan, H Ullah, PCMF Castilho… - Critical Reviews in …, 2020 - Taylor & Francis
Being a transcription factor, NF-κB regulates gene expressions involving cell survival and
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …