The cytokine interleukin‐31 has been implicated in the pathophysiology of multiple atopic
disorders such as atopic dermatitis (AD), allergic rhinitis, and airway hyper‐reactivity. In AD …

Oncostatin M (OSM) and interleukin-31 (IL-31) are two cytokines belonging to the IL-6 family
which share a common signaling receptor subunit, the OSM receptor beta (OSMRβ). Both of …

Cytokines play a very important role in nearly all aspects of inflammation and immunity. The
term'interleukin'(IL) has been used to describe a group of cytokines with complex …

Pruritus represents one of the most common symptoms in dermatology and general
medicine. Chronic pruritus severely impairs the quality of life of affected patients. During the …

BACKGROUND: Atopic dermatitis (AD) is an inflammatory skin disease affecting 10% to
20% of children and 1% to 3% of adults in industrialized countries. Enhanced expression of …

Systemic sclerosis (SSc) is a chronic multisystem disorder characterized by fibrosis and
autoimmunity. Interleukin (IL)-31 has been implicated in fibrosis and T helper (Th) 2 immune …

Several diseases of the airways have a strong component of allergic inflammation in their
cause, including allergic rhinitis, asthma, polypoid chronic rhinosinusitis, eosinophilic …

Oncostatin M is a secreted cytokine involved in homeostasis and in diseases involving
chronic inflammation. It is a member of the gp130 family of cytokines that have pleiotropic …

Interleukin-31, produced mainly by activated CD4+ T cells, is a newly discovered member of
the gp130/IL-6 cytokine family. Unlike all the other family members, IL-31 does not engage …

Cardiac healing after myocardial ischemia depends on the recruitment and local expansion
of myeloid cells, particularly macrophages. Here we identify Reg3β as an essential regulator …