Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

Necrotizing enterocolitis, gut microbes, and sepsis

JW Duess, ME Sampah, CM Lopez, K Tsuboi… - Gut …, 2023 - Taylor & Francis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the
leading cause of death and disability from gastrointestinal disease in this vulnerable …

Probiotics for the management of pediatric gastrointestinal disorders: position paper of the ESPGHAN Special Interest Group on Gut Microbiota and Modifications

H Szajewska, RB Canani, M Domellöf… - Journal of pediatric …, 2023 - journals.lww.com
Background: Probiotics, defined as live microorganisms that, when administered in
adequate amounts, confer a health benefit on the host, are widely used despite uncertainty …

Probiotics to improve the gut microbiome in premature infants: are we there yet?

EM Mercer, MC Arrieta - Gut microbes, 2023 - Taylor & Francis
Gut microbiome maturation in infants born prematurely is uniquely influenced by the
physiological, clinical, and environmental factors surrounding preterm birth and early life …

The influence of nutrition on intestinal permeability and the microbiome in health and disease

O Inczefi, P Bacsur, T Resál, C Keresztes… - Frontiers in …, 2022 - frontiersin.org
The leakage of the intestinal barrier and the disruption of the gut microbiome are
increasingly recognized as key factors in different pathophysiological conditions, such as …

Probiotics, prebiotics, and synbiotics for the prevention of necrotizing enterocolitis

K Murphy, RP Ross, CA Ryan, EM Dempsey… - Frontiers in …, 2021 - frontiersin.org
Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in preterm infants.
The exact mechanism by which NEC develops is poorly understood however there is …

[HTML][HTML] Early gut microbiota intervention in premature infants: Application perspectives

Q Xiang, X Yan, W Shi, H Li, K Zhou - Journal of Advanced Research, 2023 - Elsevier
Background Preterm birth is the leading cause of death in children under the age of five.
One of the major factors contributing to the high risk of diseases and deaths in premature …

Microbiome-targeting therapies in the neonatal intensive care unit: safety and efficacy

A DeVeaux, J Ryou, G Dantas, BB Warner, PI Tarr - Gut microbes, 2023 - Taylor & Francis
Microbiome-targeting therapies have received great attention as approaches to prevent
disease in infants born preterm, but their safety and efficacy remain uncertain. Here we …

Growth and neuro-developmental outcomes of probiotic supplemented preterm infants—a systematic review and meta-analysis

H Panchal, G Athalye-Jape, S Rao… - European Journal of …, 2023 - nature.com
Gut dysbiosis is associated with sepsis and necrotizing enterocolitis in preterm infants,
which can adversely affect long-term growth and neurodevelopment. We aimed to …

The role of diet and nutritional interventions for the Infant Gut Microbiome

G Catassi, M Aloi, V Giorgio, A Gasbarrini… - Nutrients, 2024 - mdpi.com
The infant gut microbiome plays a key role in the healthy development of the human
organism and appears to be influenced by dietary practices through multiple pathways. First …