Glomerular hyperfiltration is a phenomenon that can occur in various clinical conditions
including kidney disease. No single definition of glomerular hyperfiltration has been agreed …

Functional foods describe the importance of foods in promoting health and preventing
diseases aside their primary role of providing the body with the required amount of essential …

To determine whether the cardiovascular effect of 1, 25 (OH) 2 D is dependent on calcium
and/or phosphorus, mice with targeted deletion of the 25 (OH) D 1α-hydroxylase and their …

We investigated whether aliskiren, a direct renin inhibitor, improves NO bioavailability and
protects against spontaneous atherosclerotic changes. We also examined the effects of …

Angiotensin I-converting enzyme (ACE) inhibitors derived from foods are valuable
auxiliaries to agents such as captopril. Eight highly functional ACE inhibitory peptides from …

Experimental and clinical studies impressively demonstrate that angiotensin-converting
enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) significantly reduce …

Renin maintains blood pressure through vasoconstriction when there is inadequate salt to
maintain volume. In populations where blood pressure is more often high than low, and …

Angiotensin (Ang) II, the main effector of the renin–angiotensin system, has been implicated
in the pathogenesis of vascular diseases. Ang-(1–7) binds to the G protein-coupled Mas …

Growing evidence has shown that NLRP3 inflammasome activation promotes the
development of tubulointerstitial inflammation and progression of renal injury. We previously …

The renin angiotensin system (RAS) consists of the systemic hormone system, critically
involved in regulation and homeostasis of normal physiological functions [ie blood pressure …