RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy
T Makovec - Radiology and oncology, 2019 - sciendo.com
Background. Platinum-based anticancer drugs are widely used in the chemotherapy of
human neoplasms. The major obstacle for the clinical use of this class of drugs is the …
human neoplasms. The major obstacle for the clinical use of this class of drugs is the …
Nanocarrier-based systems for targeted and site specific therapeutic delivery
Systemic drug delivery methods such as oral or parenteral administration of free drugs
possess relatively low treatment efficiency and marked adverse side effects. The use of …
possess relatively low treatment efficiency and marked adverse side effects. The use of …
Employing siRNA tool and its delivery platforms in suppressing cisplatin resistance: approaching to a new era of cancer chemotherapy
Although chemotherapy is a first option in treatment of cancer patients, drug resistance has
led to its failure, requiring strategies to overcome it. Cancer cells are capable of switching …
led to its failure, requiring strategies to overcome it. Cancer cells are capable of switching …
Nanomedicines for endometriosis: lessons learned from cancer research
Endometriosis is an incurable gynecological disease characterized by the abnormal growth
of endometrium‐like tissue, characteristic of the uterine lining, outside of the uterine cavity …
of endometrium‐like tissue, characteristic of the uterine lining, outside of the uterine cavity …
Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy
X Huang, M Qiu, T Wang, B Li, S Zhang… - Journal of …, 2022 - Springer
Background Ovarian cancer is the most lethal gynecological cancer which is characterized
by extensive peritoneal implantation metastasis and malignant ascites. Despite advances in …
by extensive peritoneal implantation metastasis and malignant ascites. Despite advances in …
An advanced thermal decomposition method to produce magnetic nanoparticles with ultrahigh heating efficiency for systemic magnetic hyperthermia
Due to the limited heating efficiency of available magnetic nanoparticles, it is difficult to
achieve therapeutic temperatures above 44° C in relatively inaccessible tumors during …
achieve therapeutic temperatures above 44° C in relatively inaccessible tumors during …
A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches
Background Despite tremendous advancements in cancer treatment delivery, we are still far
from achieving successful cancer prognosis and cure. The use of new nanocarriers for site …
from achieving successful cancer prognosis and cure. The use of new nanocarriers for site …
Nanoparticle‐Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer‐Associated Cachexia
This study presents the first messenger RNA (mRNA) therapy for metastatic ovarian cancer
and cachexia‐induced muscle wasting based on lipid nanoparticles that deliver follistatin …
and cachexia‐induced muscle wasting based on lipid nanoparticles that deliver follistatin …
Development and perspectives: multifunctional nucleic acid nanomedicines for treatment of gynecological cancers
Gynecological malignancies are a significant cause of morbidity and mortality across the
globe. Due to delayed presentation, gynecological cancer patients are often referred late in …
globe. Due to delayed presentation, gynecological cancer patients are often referred late in …