Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

T Lazarević, A Rilak, ŽD Bugarčić - European journal of medicinal chemistry, 2017 - Elsevier
Metallodrugs offer potential for unique mechanism of drug action based on the choice of the
metal, its oxidation state, the types and number of coordinated ligands and the coordination …

Chemistry and reactivity of ruthenium (II) complexes: DNA/protein binding mode and anticancer activity are related to the complex structure

AR Simović, R Masnikosa, I Bratsos… - Coordination Chemistry …, 2019 - Elsevier
In this review we summarize our work on development of Ru complexes with potential
antitumor activity, which was performed over the last few years. In order to establish the …

Digital supply chain performance metrics: a literature review

F Rasool, M Greco, M Grimaldi - Measuring Business Excellence, 2022 - emerald.com
Purpose In the previous decade, a substantial amount of research has been undertaken to
measure the digitalized supply chain (DSC) performance. This paper aims to present a …

Ruthenium-based antitumor drugs and delivery systems from monotherapy to combination therapy

Y Lu, D Zhu, Q Le, Y Wang, W Wang - Nanoscale, 2022 - pubs.rsc.org
Ruthenium complex is an important compound group for antitumor drug research and
development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered …

A Bioprinted Tubular Intestine Model Using a Colon‐Specific Extracellular Matrix Bioink

H Han, Y Park, Y Choi, U Yong, B Kang… - Advanced …, 2022 - Wiley Online Library
Tremendous advances have been made toward accurate recapitulation of the human
intestinal system in vitro to understand its developmental process, and disease progression …

New ruthenium (II) complexes with quinone diimine and substituted bipyridine as inert ligands: synthesis, characterization, mechanism of action, DNA/HSA binding …

M Međedović, AR Simović, D Ćoćić, L Senft… - Dalton …, 2023 - pubs.rsc.org
This paper presents the synthesis and structural characterization of a series of new
ruthenium (II) complexes 1–7, with the general formula mer-[RuL3 (N–N) Cl] Cl, where L is 2 …

Ruthenium complexes with mono- or bis-heterocyclic chelates: DNA/BSA binding, antioxidant and anticancer studies

S Maikoo, A Chakraborty, N Vukea… - Journal of …, 2021 - Taylor & Francis
Deoxyribonucleic acid (DNA) and bovine serum albumin (BSA) binding interactions for a
series of ruthenium heterocyclic complexes were monitored using ultraviolet-visible (UV-Vis) …

Antitumor activity of ruthenium (II) terpyridine complexes towards colon cancer cells in vitro and in vivo

M Savic, A Arsenijevic, J Milovanovic, B Stojanovic… - Molecules, 2020 - mdpi.com
Ruthenium complexes have attracted considerable interest as potential antitumor agents.
Therefore, antitumor activity and systemic toxicity of ruthenium (II) terpyridine complexes …

[HTML][HTML] Antitumor activity of tridentate pincer and related metal complexes

S Wu, Z Wu, Q Ge, X Zheng, Z Yang - Organic & Biomolecular …, 2021 - pubs.rsc.org
Pincer complexes featuring tunable tridentate ligand frameworks are one of the most actively
studied classes of metal-based complexes. Currently, growing attention is devoted to the …

Impact of aromaticity on anticancer activity of polypyridyl ruthenium (II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity

P Čanović, AR Simović, S Radisavljević… - JBIC Journal of …, 2017 - Springer
With the aim of assessing how the aromaticity of the inert chelating ligand can influence the
activity of ruthenium (II) polypyridyl complexes, two new monofunctional ruthenium (II) …