Social determinants of cardiovascular disease
Social determinants of health (SDoH), which encompass the economic, social,
environmental, and psychosocial factors that influence health, play a significant role in the …
environmental, and psychosocial factors that influence health, play a significant role in the …
[HTML][HTML] Stress-induced biological aging: A review and guide for research priorities
LR Polsky, KE Rentscher, JE Carroll - Brain, behavior, and immunity, 2022 - Elsevier
Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …
response cascade, has been associated with an increased risk of early onset of age-related …
[HTML][HTML] The energetic cost of allostasis and allostatic load
Chronic psychosocial stress increases disease risk and mortality, but the underlying
mechanisms remain largely unclear. Here we outline an energy-based model for the …
mechanisms remain largely unclear. Here we outline an energy-based model for the …
Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care
A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …
By what molecular mechanisms do social determinants impact cardiometabolic risk?
While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …
Prenatal maternal stress is associated with site-specific and age acceleration changes in maternal and newborn DNA methylation
Prenatal maternal stress has a negative impact on child health but the mechanisms through
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …
Applying a life course biological age framework to improving the care of individuals with adult cancers: review and research recommendations
JS Mandelblatt, TA Ahles, ME Lippman, C Isaacs… - JAMA …, 2021 - jamanetwork.com
Importance The practice of oncology will increasingly involve the care of a growing
population of individuals with midlife and late-life cancers. Managing cancer in these …
population of individuals with midlife and late-life cancers. Managing cancer in these …
[HTML][HTML] The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure
F Dammering, J Martins, K Dittrich, D Czamara… - Neurobiology of …, 2021 - Elsevier
Background Studies reporting accelerated ageing in children with affective disorders or
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
Deficit accumulation frailty trajectories of older breast cancer survivors and non-cancer controls: the thinking and living with cancer study
Background We evaluated deficit accumulation and how deficits affected cognition and
physical activity among breast cancer survivors and non-cancer controls. Methods Newly …
physical activity among breast cancer survivors and non-cancer controls. Methods Newly …
Effects of the social environment on vertebrate fitness and health in nature: Moving beyond the stress axis
Social interactions are a ubiquitous feature of the lives of vertebrate species. These may be
cooperative or competitive, and shape the dynamics of social systems, with profound effects …
cooperative or competitive, and shape the dynamics of social systems, with profound effects …