Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

RNA-based antiviral immunity

SW Ding - Nature Reviews Immunology, 2010 - nature.com
In eukaryotic RNA-based antiviral immunity, viral double-stranded RNA is recognized as a
pathogen-associated molecular pattern and processed into small interfering RNAs (siRNAs) …

Origins and evolution of the global RNA virome

YI Wolf, D Kazlauskas, J Iranzo, A Lucía-Sanz, JH Kuhn… - MBio, 2018 - Am Soc Microbiol
Viruses with RNA genomes dominate the eukaryotic virome, reaching enormous diversity in
animals and plants. The recent advances of metaviromics prompted us to perform a detailed …

A selective autophagy receptor VISP1 induces symptom recovery by targeting viral silencing suppressors

X Tong, JJ Zhao, YL Feng, JZ Zou, J Ye, J Liu… - Nature …, 2023 - nature.com
Selective autophagy is a double-edged sword in antiviral immunity and regulated by various
autophagy receptors. However, it remains unclear how to balance the opposite roles by one …

The good viruses: viral mutualistic symbioses

MJ Roossinck - Nature Reviews Microbiology, 2011 - nature.com
Although viruses are most often studied as pathogens, many are beneficial to their hosts,
providing essential functions in some cases and conditionally beneficial functions in others …

The Tomato Yellow Leaf Curl Virus Resistance Genes Ty-1 and Ty-3 Are Allelic and Code for DFDGD-Class RNA–Dependent RNA Polymerases

MG Verlaan, SF Hutton, RM Ibrahem, R Kormelink… - PLoS …, 2013 - journals.plos.org
Tomato Yellow Leaf Curl Virus Disease incited by Tomato yellow leaf curl virus (TYLCV)
causes huge losses in tomato production worldwide and is caused by different related …

Viral suppressors of RNA silencing

J Burgyán, Z Havelda - Trends in plant science, 2011 - cell.com
The infection and replication of viruses in the host induce diverse mechanisms for combating
viral infection. One of the best-studied antiviral defence mechanisms is based on RNA …

Viruses and miRNAs: more friends than foes

P Bruscella, S Bottini, C Baudesson… - Frontiers in …, 2017 - frontiersin.org
There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the
replication and propagation of viruses. Expression or targeting of host miRNAs can be …

[HTML][HTML] Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

EV Koonin, P Starokadomskyy - Studies in history and philosophy of …, 2016 - Elsevier
The question whether or not “viruses are alive” has caused considerable debate over many
years. Yet, the question is effectively without substance because the answer depends …

The family Narnaviridae: simplest of RNA viruses

BI Hillman, G Cai - Advances in virus research, 2013 - Elsevier
Members of the virus family Narnaviridae contain the simplest genomes of any RNA virus,
ranging from 2.3 to 3.6 kb and encoding only a single polypeptide that has an RNA …