Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
RNA-based antiviral immunity
SW Ding - Nature Reviews Immunology, 2010 - nature.com
In eukaryotic RNA-based antiviral immunity, viral double-stranded RNA is recognized as a
pathogen-associated molecular pattern and processed into small interfering RNAs (siRNAs) …
pathogen-associated molecular pattern and processed into small interfering RNAs (siRNAs) …
Origins and evolution of the global RNA virome
Viruses with RNA genomes dominate the eukaryotic virome, reaching enormous diversity in
animals and plants. The recent advances of metaviromics prompted us to perform a detailed …
animals and plants. The recent advances of metaviromics prompted us to perform a detailed …
A selective autophagy receptor VISP1 induces symptom recovery by targeting viral silencing suppressors
X Tong, JJ Zhao, YL Feng, JZ Zou, J Ye, J Liu… - Nature …, 2023 - nature.com
Selective autophagy is a double-edged sword in antiviral immunity and regulated by various
autophagy receptors. However, it remains unclear how to balance the opposite roles by one …
autophagy receptors. However, it remains unclear how to balance the opposite roles by one …
The good viruses: viral mutualistic symbioses
MJ Roossinck - Nature Reviews Microbiology, 2011 - nature.com
Although viruses are most often studied as pathogens, many are beneficial to their hosts,
providing essential functions in some cases and conditionally beneficial functions in others …
providing essential functions in some cases and conditionally beneficial functions in others …
The Tomato Yellow Leaf Curl Virus Resistance Genes Ty-1 and Ty-3 Are Allelic and Code for DFDGD-Class RNA–Dependent RNA Polymerases
MG Verlaan, SF Hutton, RM Ibrahem, R Kormelink… - PLoS …, 2013 - journals.plos.org
Tomato Yellow Leaf Curl Virus Disease incited by Tomato yellow leaf curl virus (TYLCV)
causes huge losses in tomato production worldwide and is caused by different related …
causes huge losses in tomato production worldwide and is caused by different related …
Viral suppressors of RNA silencing
The infection and replication of viruses in the host induce diverse mechanisms for combating
viral infection. One of the best-studied antiviral defence mechanisms is based on RNA …
viral infection. One of the best-studied antiviral defence mechanisms is based on RNA …
Viruses and miRNAs: more friends than foes
P Bruscella, S Bottini, C Baudesson… - Frontiers in …, 2017 - frontiersin.org
There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the
replication and propagation of viruses. Expression or targeting of host miRNAs can be …
replication and propagation of viruses. Expression or targeting of host miRNAs can be …
[HTML][HTML] Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question
EV Koonin, P Starokadomskyy - Studies in history and philosophy of …, 2016 - Elsevier
The question whether or not “viruses are alive” has caused considerable debate over many
years. Yet, the question is effectively without substance because the answer depends …
years. Yet, the question is effectively without substance because the answer depends …
The family Narnaviridae: simplest of RNA viruses
BI Hillman, G Cai - Advances in virus research, 2013 - Elsevier
Members of the virus family Narnaviridae contain the simplest genomes of any RNA virus,
ranging from 2.3 to 3.6 kb and encoding only a single polypeptide that has an RNA …
ranging from 2.3 to 3.6 kb and encoding only a single polypeptide that has an RNA …