Pathophysiology and immune dysfunction in endometriosis

SH Ahn, SP Monsanto, C Miller… - BioMed research …, 2015 - Wiley Online Library
Endometriosis is an estrogen‐dependent, chronic, proinflammatory disease prevalent in
10% of women of reproductive age worldwide. Characterized by the growth of endometrium …

Indoleamine 2, 3-dioxygenase and its therapeutic inhibition in cancer

GC Prendergast, WJ Malachowski, A Mondal… - International review of …, 2018 - Elsevier
The tryptophan catabolic enzyme indoleamine 2, 3-dioxygenase-1 (IDO1) has attracted
enormous attention in driving cancer immunosuppression, neovascularization, and …

3D cell printing of in vitro stabilized skin model and in vivo pre-vascularized skin patch using tissue-specific extracellular matrix bioink: A step towards advanced skin …

BS Kim, YW Kwon, JS Kong, GT Park, G Gao, W Han… - Biomaterials, 2018 - Elsevier
Abstract 3D cell-printing technique has been under spotlight as an appealing biofabrication
platform due to its ability to precisely pattern living cells in pre-defined spatial locations. In …

Vascularization is the key challenge in tissue engineering

EC Novosel, C Kleinhans, PJ Kluger - Advanced drug delivery reviews, 2011 - Elsevier
The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …

Insights into endothelial progenitor cells: origin, classification, potentials, and prospects

H Chopra, MK Hung, DL Kwong… - Stem cells …, 2018 - Wiley Online Library
With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

T Rademakers, JM Horvath… - Journal of tissue …, 2019 - Wiley Online Library
The field of tissue engineering is making great strides in developing replacement tissue
grafts for clinical use, marked by the rapid development of novel biomaterials, their improved …

Characterization of vascular disruption and blood–spinal cord barrier permeability following traumatic spinal cord injury

SA Figley, R Khosravi, JM Legasto, YF Tseng… - Journal of …, 2014 - liebertpub.com
Significant vascular changes occur subsequent to spinal cord injury (SCI), which contribute
to progressive pathophysiology. In the present study, we used female Wistar rats (300–350 …

Origin of endothelial progenitors in human postnatal bone marrow

M Reyes, A Dudek, B Jahagirdar… - The Journal of …, 2002 - Am Soc Clin Investig
This study demonstrates that a CD34–, vascular endothelial cadherin–(VE-cadherin–),
AC133+, and fetal liver kinase+ (Flk1+) multipotent adult progenitor cell (MAPC) that …

In vitro assays of angiogenesis for assessment of angiogenic and anti-angiogenic agents

AM Goodwin - Microvascular research, 2007 - Elsevier
Blood vessels, either in insufficient numbers or in excess, contribute to the pathogenesis of
many diseases. Agents that stimulate angiogenesis can improve blood flow in patients with …

Vascularization of three-dimensional engineered tissues for regenerative medicine applications

JJ Kim, L Hou, NF Huang - Acta biomaterialia, 2016 - Elsevier
Engineering of three-dimensional (3D) tissues is a promising approach for restoring
diseased or dysfunctional myocardium with a functional replacement. However, a major …