Pigs (Sus Scrofa) in Biomedical Research
WG Bergen - Recent Advances in Animal Nutrition and Metabolism, 2022 - Springer
Much of biomedical oriented research is conducted with animal models. Over the years,
rodents (primarily rats and mice) have emerged as the preferred species for basic …
rodents (primarily rats and mice) have emerged as the preferred species for basic …
[HTML][HTML] Diet-induced rabbit models for the study of metabolic syndrome
WM Lozano, OJ Arias-Mutis, CJ Calvo, FJ Chorro… - Animals, 2019 - mdpi.com
Simple Summary In recent years, obesity and metabolic syndrome (MetS) have become
more prevalent owing to increased unhealthy habits and sedentary lifestyles, becoming …
more prevalent owing to increased unhealthy habits and sedentary lifestyles, becoming …
Novel göttingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities
A lack of preclinical large animal models of heart failure with preserved ejection fraction
(HFpEF) that recapitulate this comorbid-laden syndrome has led to the inability to tease out …
(HFpEF) that recapitulate this comorbid-laden syndrome has led to the inability to tease out …
Porcine germline genome engineering
Germline editing, the process by which the genome of an individual is edited in such a way
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …
Swine disease models for optimal vascular engineering
Swine disease models are essential for mimicry of human metabolic and vascular
pathophysiology, thereby enabling high-fidelity translation to human medicine. The …
pathophysiology, thereby enabling high-fidelity translation to human medicine. The …
[HTML][HTML] Identification of genomic regions, genetic variants and gene networks regulating candidate genes for lipid metabolism in pig muscle
M Passols, F Llobet-Cabau, C Sebastià, A Castelló… - animal, 2023 - Elsevier
The intramuscular fat content and fatty acid composition of porcine meat have a significant
impact on its quality and nutritional value. This research aimed to investigate the expression …
impact on its quality and nutritional value. This research aimed to investigate the expression …
[HTML][HTML] The genome of the naturally evolved obesity-prone Ossabaw miniature pig
The feral pigs of Ossabaw Island (USA) have an outstanding propensity to obesity and
develop complete metabolic syndrome (MetS) upon prolonged high energy dieting. We now …
develop complete metabolic syndrome (MetS) upon prolonged high energy dieting. We now …
[HTML][HTML] Endothelial dysfunction, atherosclerosis, and increase of von Willebrand factor and factor VIII: a randomized controlled trial in swine
It is well known that high von Willebrand factor (VWF) and factor VIII (FVIII) levels are
associated with an increased risk of cardiovascular disease. It is still debated whether VWF …
associated with an increased risk of cardiovascular disease. It is still debated whether VWF …
Obesity development in a miniature Yucatan pig model: a multi-compartmental metabolomics study on cloned and normal pigs fed restricted or ad libitum high-energy …
Miniature-pig models for human metabolic disorders such as obesity and metabolic
syndrome are gaining popularity. However, in-depth knowledge on the phenotypic and …
syndrome are gaining popularity. However, in-depth knowledge on the phenotypic and …
[HTML][HTML] Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
L Criado-Mesas, M Ballester, D Crespo-Piazuelo… - Scientific reports, 2020 - nature.com
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its
nutritional value. The present work aimed to identify genomic variants regulating the …
nutritional value. The present work aimed to identify genomic variants regulating the …