Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Low back pain (LBP), a prevalent and costly disease around the world, is predominantly
caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial …

The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Rationale: Atherosclerotic cardiovascular diseases are the leading cause of mortality
worldwide. Atherosclerotic cardiovascular diseases are considered as chronic inflammation …

An increasing number of studies show how changes in intracellular metabolic pathways
alter tumor and immune cell function. However, little information about metabolic changes in …

With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …

Suppressing inflammation has been the primary focus of therapies in autoimmune rheumatic
diseases (AIRDs), including rheumatoid arthritis and systemic lupus erythematosus …

Deregulated NF-κB signalling is implicated in the pathogenesis of numerous human
inflammatory disorders and malignancies. Consequently, the NF-κB pathway has attracted …