The mammalian transcriptome and the function of non-coding DNA sequences

SA Shabalina, NA Spiridonov - Genome biology, 2004 - Springer
For decades, researchers have focused most of their attention on protein-coding genes and
proteins. With the completion of the human and mouse genomes and the accumulation of …

Ribosome profiling reveals resemblance between long non-coding RNAs and 5′ leaders of coding RNAs

GL Chew, A Pauli, JL Rinn, A Regev… - …, 2013 - journals.biologists.com
Large-scale genomics and computational approaches have identified thousands of putative
long non-coding RNAs (lncRNAs). It has been controversial, however, as to what fraction of …

Initial sequence and comparative analysis of the cat genome

JU Pontius, JC Mullikin, DR Smith… - Genome …, 2007 - genome.cshlp.org
The genome sequence (1.9-fold coverage) of an inbred Abyssinian domestic cat was
assembled, mapped, and annotated with a comparative approach that involved cross …

Yeast as a touchstone in post-genomic research: strategies for integrative analysis in functional genomics

JI Castrillo, SG Oliver - BMB Reports, 2004 - koreascience.kr
The new complexity arising from the genome sequencing projects requires new
comprehensive post-genomic strategies: advanced studies in regulatory mechanisms …

Transcriptional interference between convergent promoters caused by elongation over the promoter

BP Callen, KE Shearwin, JB Egan - Molecular cell, 2004 - cell.com
Transcriptional interference with convergent transcription from face-to-face promoters is a
potentially important form of gene regulation in all organisms. Using LacZ reporter studies …

Antisense transcripts with FANTOM2 clone set and their implications for gene regulation

H Kiyosawa, I Yamanaka, N Osato, S Kondo… - Genome …, 2003 - genome.cshlp.org
We have used the FANTOM2 mouse cDNA set (60,770 clones), public mRNA data, and
mouse genome sequence data to identify 2481 pairs of sense–antisense transcripts and …

Sp8 is crucial for limb outgrowth and neuropore closure

SM Bell, CM Schreiner, RR Waclaw… - Proceedings of the …, 2003 - National Acad Sciences
In this report we describe the developmental expression and function of Sp8, a member of
the Sp family of zinc finger transcription factors, and provide evidence that the legless …

Low conservation of alternative splicing patterns in the human and mouse genomes

RN Nurtdinov, II Artamonova, AA Mironov… - Human Molecular …, 2003 - academic.oup.com
Alternative splicing has recently emerged as a major mechanism of generating protein
diversity in higher eukaryotes. We compared alternative splicing isoforms of 166 pairs of …

Full-length cDNA

T Isogai, T Sugiyama, T Otsuki, A Wakamatsu… - US Patent …, 2005 - Google Patents
2003-01-02 Assigned to HELIX RESEARCH INSTITUTE reassignment HELIX RESEARCH
INSTITUTE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …

Antisense transcripts with rice full-length cDNAs

N Osato, H Yamada, K Satoh, H Ooka, M Yamamoto… - Genome Biology, 2003 - Springer
Background Natural antisense transcripts control gene expression through post-
transcriptional gene silencing by annealing to the complementary sequence of the sense …