Synthesis, characterization, DFT, docking studies and molecular dynamics of some 3-phenyl-5-furan isoxazole derivatives as anti-inflammatory and anti-ulcer agents
A vast number of nitrogen heterocyclic derivatives comprising oxygen atom is considered as
a valuable combination of therapeutic agents in curative chemistry. In particular, isoxazole, a …
a valuable combination of therapeutic agents in curative chemistry. In particular, isoxazole, a …
Design-based synthesis, molecular docking analysis of an anti-inflammatory drug, and geometrical optimization and interaction energy studies of an indole acetamide …
The new indole acetamide, N-(2-(2-(4-Chlorophenoxy) acetamido) phenyl)-2-carboxamide-
1H-indole (5) has been synthesized with good yield by stirring the compound N-(2 …
1H-indole (5) has been synthesized with good yield by stirring the compound N-(2 …
Synthesis, crystal structure and 3D energy frameworks of ethyl 2-[5-nitro-2-oxopyridine-1 (2H)-yl] acetate: Hirshfeld surface analysis and DFT calculations
Pyridine derivatives with different heterocyclic nucleus have shown potent pharmacological
properties as a part from the previously marketed drugs. The title compound, ethyl 2-[5-nitro …
properties as a part from the previously marketed drugs. The title compound, ethyl 2-[5-nitro …
Synthesis, in silico study and in vitro anti-microbial evaluation of some new N-benzoyl-N'-[2-(4-chloro-phenoxy)-acetyl]-hydrazides analogs
FH Al-Ostoot, YHE Mohammed… - Journal of Applied …, 2019 - japsonline.com
In bacterial resistance duty, the prompt increase against existent anti-microbial drugs is a
challenging universal health problem. Bacteria represent a highly significant threat globally …
challenging universal health problem. Bacteria represent a highly significant threat globally …
Synthesis, structural characterization, and DFT studies of anti-cancer drug N-(2-Aminophenyl)-2-(4-bromophenoxy) acetamide
SN Chandana, FH Al-Ostoot, YHE Mohammed… - Heliyon, 2021 - cell.com
Drug design is an integrated and developing system that portends an era of a novel and
safe tailored drugs. It involves studying the effects of biologically active synthetic, semi …
safe tailored drugs. It involves studying the effects of biologically active synthetic, semi …
Synthesis, structure and molecular docking analysis of an anticancer drug of N-(2-aminophenyl)-2-(2-isopropylphenoxy) acetamide
G Sharma, S Anthal, DV Geetha… - … Crystals and Liquid …, 2018 - Taylor & Francis
Abstract N-(2-aminophenyl)-2-(2-isopropylphenoxy) acetamide (3) has been synthesized in
good yield by stirring compound ethyl 2-(2-isopropylphenoxy) acetic acid (1), with, 2 …
good yield by stirring compound ethyl 2-(2-isopropylphenoxy) acetic acid (1), with, 2 …
[HTML][HTML] A potent anesthetic drug salt: experimental and computational studies
NK Manjunatha, NN Alzubaidy, U Likhitha… - Journal of Molecular …, 2022 - Elsevier
The title compound Ethyl 4-aminobenzoate–3, 5-dinitrosalicylate salt [ES] has been
synthesized, crystallized and characterized using FTIR, 1 H NMR, 13 C NMR and confirmed …
synthesized, crystallized and characterized using FTIR, 1 H NMR, 13 C NMR and confirmed …
Synthesis, spectroscopic and X-ray crystallographic analysis of N-(2-(2-(4-chlorophenoxy) acetamido) phenyl)-1H-indole-2-carboxamide
FH Al-Ostoot, J Stondus, S Anthal… - European Journal of …, 2019 - eurjchem.com
Medicinal chemistry of indole analogs constitutes important therapeutic agents with anti-
oxidant, anti-HIV and anti-cancer activities. Indole nucleus is frequently found in synthetic …
oxidant, anti-HIV and anti-cancer activities. Indole nucleus is frequently found in synthetic …
X–ray crystal structure, Hirshfeld surface analysis, DFT and electronic properties of (E)–4–chloro–N′–(2, 4–dihydroxy–benzylidene) benzohydrazide
C Arunagiri, AG Anitha, A Subashini… - Chemical Data …, 2019 - Elsevier
A new compound of the title Schiff base (C 14 H 11 ClN 2 O 3) was synthesized and
characterized by using spectroscopic tools such as IR, NMR (1 H and 13 C), UV visible …
characterized by using spectroscopic tools such as IR, NMR (1 H and 13 C), UV visible …
Crystal structure, quantum chemical and Hirshfeld surface analysis of N-ethyl-6-methyl-2-oxo-4-phenyl-1, 2, 3, 4-tetrahydropyrimidine-5-carboxamide
GNA Kumar, U Katrahalli - Chemical Data Collections, 2020 - Elsevier
The molecular structure of N-ethyl-6-methyl-2-oxo-4-phenyl-1, 2, 3, 4-tetrahydropyrimidine-5-
carboxamide (C 14 H 16 N 3 O 2) has been investigated via single crystal X-ray diffraction …
carboxamide (C 14 H 16 N 3 O 2) has been investigated via single crystal X-ray diffraction …