Based on its effects on both tumour cell intrinsic malignant properties as well as anti-tumour
immune responses, tryptophan catabolism has emerged as an important metabolic regulator …

Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …

Aims Poisoning with aluminium phosphide (AlP) commonly has a high rate of mortality and
morbidities. Phosphine gas is the main cause of AlP poisoning that has deleterious effect on …

The exposure of benzo [a] pyrene (BaP) in recent times is rather unavoidable than ever
before. BaP emissions are sourced majorly from anthropogenic rather than natural …

Ferroptosis is a type of iron-mediated cell death merging cell metabolism, redox status, and
human disease. Reactive oxygen species (ROS) are formed after exposure to xenobiotics …

Despite numerous studies on the mechanisms of cigarette smoking toxicity over the past
three decades, some aspects remain obscure. Recent developments have drawn attention …

Aims Although chemotherapeutic agents have highly beneficial effects against cancer, they
disturb the body's normal homeostasis. One of the critical side effects of chemotherapeutic …

Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of
only 1–4%. Integrin-mediated cell adhesion is critical for the initiation, progression, and …

Progesterone receptor membrane component 1 (PGRMC1) has been shown to regulate
some cancer hallmarks. Progesterone (P4) evokes intracellular calcium (Ca2+) changes in …

Glioblastoma is the most frequent and aggressive primary astrocytoma in adults. The high
migration ability of the tumor cells is an important reason for the high recurrence rate and …