Health functionality of apigenin: A review

F Ali, Rahul, F Naz, S Jyoti… - International Journal of …, 2017 - Taylor & Francis
Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

NS Yarla, A Bishayee, G Sethi, P Reddanna… - Seminars in cancer …, 2016 - Elsevier
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK-NF-κB-TNF-α and TGF-β1-MAPK-fibronectin pathways

S Malik, K Suchal, SI Khan, J Bhatia… - American Journal …, 2017 - journals.physiology.org
Diabetic nephropathy (DN), a microvascular complication of diabetes, has emerged as an
important health problem worldwide. There is strong evidence to suggest that oxidative …

Pharmacokinetic properties and drug interactions of apigenin, a natural flavone

D Tang, K Chen, L Huang, J Li - Expert opinion on drug metabolism …, 2017 - Taylor & Francis
Introduction: Apigenin, a natural flavone, is widely distributed in plants such as celery,
parsley and chamomile. It is present principally as glycosylated in nature. Higher intake of …

Rationalizing the therapeutic potential of apigenin against cancer

SA Ahmed, D Parama, E Daimari, S Girisa, K Banik… - Life sciences, 2021 - Elsevier
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …

Therapeutical properties of apigenin: A review on the experimental evidence and basic mechanisms

Z Mushtaq, NB Sadeer, M Hussain… - … Journal of Food …, 2023 - Taylor & Francis
ABSTRACT Apigenin (4,'5, 7-trihydroxyflavone) is one of the most studied flavonoids with
low toxicity and abundantly present phenolic compound in the plant kingdom. The main …

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

AN Adham, S Abdelfatah, AM Naqishbandi… - Phytomedicine, 2021 - Elsevier
Background Apigenin is one of the most abundant dietary flavonoids that possesses multiple
bio-functions. Purpose This study was designed to determine the influence of apigenin on …

[HTML][HTML] CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal …

Y Ogura, M Kitada, J Xu, I Monno, D Koya - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Mitochondrial oxidative stress is a significant contributor to the pathogenesis of diabetic
kidney disease (DKD). We previously showed that mitochondrial oxidative stress in the …

Apigenin: A current review on its beneficial biological activities

X Zhou, F Wang, R Zhou, X Song… - Journal of Food …, 2017 - Wiley Online Library
Abstract Apigenin, identified as 4′, 5, 7‐trihydroxyflavone, is a natural flavonoid compound
present in a variety of fruits, vegetables, functional foods, and medicinal plants. Many studies …

A classical description of subnanometer resolution by atomic features in metallic structures

S Trautmann, J Aizpurua, I Götz, A Undisz, J Dellith… - Nanoscale, 2017 - pubs.rsc.org
Recent experiments have evidenced sub-nanometer resolution in plasmonic-enhanced
probe spectroscopy. Such a high resolution cannot be simply explained using the commonly …