The pathogenesis of rheumatoid arthritis
S Alivernini, GS Firestein, IB McInnes - Immunity, 2022 - cell.com
Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
[HTML][HTML] Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs
W Jing, C Liu, C Su, L Liu, P Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
Cellular metabolic adaptations in rheumatoid arthritis and their therapeutic implications
Activation of endothelium and immune cells is fundamental to the initiation of autoimmune
diseases such as rheumatoid arthritis (RA), and it results in trans-endothelial cell migration …
diseases such as rheumatoid arthritis (RA), and it results in trans-endothelial cell migration …
[PDF][PDF] Pathogenesis of rheumatoid arthritis: one year in review 2023
FM Mariani, I Martelli, F Pistone… - Clin Exp …, 2023 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by local and
systemic inflammation. The complex interplay between immune cells and soluble mediators …
systemic inflammation. The complex interplay between immune cells and soluble mediators …
Therapeutic effects of mesenchymal/stromal stem cells and their derived extracellular vesicles in rheumatoid arthritis
D Tsiapalis, A Floudas, T Tertel… - Stem Cells …, 2023 - academic.oup.com
Currently available therapies for rheumatoid arthritis (RA) are inadequate to alleviate the
inflammation and reduce joint damage. While the immune-regulatory effect of human …
inflammation and reduce joint damage. While the immune-regulatory effect of human …
[HTML][HTML] The search for the pathogenic T cells in the joint of rheumatoid arthritis: Which T-cell subset drives autoimmune inflammation?
H Yamada - International journal of molecular sciences, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disorder affecting systemic synovial
tissues, leading to the destruction of multiple joints. Its etiology is still unknown, but T-cell …
tissues, leading to the destruction of multiple joints. Its etiology is still unknown, but T-cell …
[HTML][HTML] Impaired immune tolerance mediated by reduced Tfr cells in rheumatoid arthritis linked to gut microbiota dysbiosis and altered metabolites
R Wu, D Wang, L Cheng, R Su, B Li, C Fan… - Arthritis Research & …, 2024 - Springer
Background Patients with rheumatoid arthritis (RA) showed impaired immune tolerance
characterized by reduced follicular regulatory T (Tfr) cells, and they also exhibited altered …
characterized by reduced follicular regulatory T (Tfr) cells, and they also exhibited altered …
Peripheral CD4+/CD8+ T cell composition distinct from healthy individuals is shared by ankylosing spondylitis and rheumatoid arthritis
L Gui, X Luo, L Zhou, Q Wei, J Gu - International Journal of …, 2023 - Wiley Online Library
Objective Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are chronic inflammatory
joint diseases, linking to the alterations of immune cells. We attempted to assess whether the …
joint diseases, linking to the alterations of immune cells. We attempted to assess whether the …
Comparison and subsets analysis of peripheral CD4+ T cells in patients with psoriasis and psoriatic arthritis
W Gao, Y Lei, X Guo, Y Luo, Z Zhang, Y Xi, W Wang… - Molecular …, 2023 - Elsevier
Psoriatic arthritis (PsA) is a disease that transformed from psoriasis (PsO), and its underlying
mechanisms are still not fully understood. Overactivation of the immune system is a key …
mechanisms are still not fully understood. Overactivation of the immune system is a key …
[HTML][HTML] Current situation and trend of non-coding RNA in rheumatoid arthritis: a review and bibliometric analysis
Z Wei, H Li, S Lv, J Yang - Frontiers in Immunology, 2024 - frontiersin.org
Background Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that
affects multiple joints and has adverse effects on various organs throughout the body, often …
affects multiple joints and has adverse effects on various organs throughout the body, often …