Representation learning of RNA velocity reveals robust cell transitions

C Qiao, Y Huang - Proceedings of the National Academy of …, 2021 - National Acad Sciences
RNA velocity is a promising technique for quantifying cellular transitions from single-cell
transcriptome experiments and revealing transient cellular dynamics among a …

Identifying cell state–associated alternative splicing events and their coregulation

CFBA Najar, P Burra, N Yosef, LF Lareau - Genome research, 2022 - genome.cshlp.org
Alternative splicing shapes the transcriptome and contributes to each cell's unique identity,
but single-cell RNA sequencing (scRNA-seq) has struggled to capture the impact of …

Uncertainty versus variability: Bayesian methods for analysis of scRNA-seq data

Y Huang, G Sanguinetti - Current Opinion in Systems Biology, 2021 - Elsevier
Single-cell 'omics technologies have the potential to revolutionize our understanding of
stochasticity and heterogeneity in biology, yet such measurements are inevitably affected by …