Pathogenesis of chagas' disease: parasite persistence and autoimmunity
ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
RL Krauth-Siegel, MA Comini - … et Biophysica Acta (BBA)-General Subjects, 2008 - Elsevier
Trypanosomes and leishmania, the causative agents of several tropical diseases, possess a
unique redox metabolism which is based on trypanothione. The bis (glutathionyl) …
unique redox metabolism which is based on trypanothione. The bis (glutathionyl) …
Full-length transcriptome assembly from RNA-Seq data without a reference genome
Massively parallel sequencing of cDNA has enabled deep and efficient probing of
transcriptomes. Current approaches for transcript reconstruction from such data often rely on …
transcriptomes. Current approaches for transcript reconstruction from such data often rely on …
[HTML][HTML] Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data
Massively-parallel cDNA sequencing has opened the way to deep and efficient probing of
transcriptomes. Current approaches for transcript reconstruction from such data often rely on …
transcriptomes. Current approaches for transcript reconstruction from such data often rely on …
TriTrypDB: a functional genomic resource for the Trypanosomatidae
M Aslett, C Aurrecoechea, M Berriman… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT TriTrypDB (http://tritrypdb. org) is an integrated database providing access to
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
The BioGRID interaction database: 2011 update
C Stark, BJ Breitkreutz, A Chatr-Aryamontri… - Nucleic acids …, 2010 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID) is a public
database that archives and disseminates genetic and protein interaction data from model …
database that archives and disseminates genetic and protein interaction data from model …
[HTML][HTML] HINT: High-quality protein interactomes and their applications in understanding human disease
Background A global map of protein-protein interactions in cellular systems provides key
insights into the workings of an organism. A repository of well-validated high-quality protein …
insights into the workings of an organism. A repository of well-validated high-quality protein …
PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium
ABSTRACT Protein Analysis THrough Evolutionary Relationships (PANTHER) is a
comprehensive software system for inferring the functions of genes based on their …
comprehensive software system for inferring the functions of genes based on their …
Small RNAs derived from snoRNAs
RJ Taft, EA Glazov, T Lassmann, Y Hayashizaki… - Rna, 2009 - rnajournal.cshlp.org
Small nucleolar RNAs (snoRNAs) guide RNA modification and are localized in nucleoli and
Cajal bodies in eukaryotic cells. Components of the RNA silencing pathway associate with …
Cajal bodies in eukaryotic cells. Components of the RNA silencing pathway associate with …
TreeFam: a curated database of phylogenetic trees of animal gene families
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to
develop a curated resource that presents the accurate evolutionary history of all animal …
develop a curated resource that presents the accurate evolutionary history of all animal …