Life-course determinants of cognitive reserve (CR) in cognitive aging and dementia–a systematic literature review

D Chapko, R McCormack, C Black, R Staff… - Aging & mental …, 2018 - Taylor & Francis
Objectives: The concept of cognitive reserve (CR) is defined as a moderator, which allows
an individual to preserve cognition despite underlying brain pathology. There is no …

What is the relationship of traumatic brain injury to dementia?

MF Mendez - Journal of Alzheimer's disease, 2017 - content.iospress.com
There is a long history linking traumatic brain injury (TBI) with the development of dementia.
Despite significant reservations, such as recall bias or concluding causality for TBI, a …

[HTML][HTML] Cognitive performance in healthy older adults relates to spontaneous switching between states of functional connectivity during rest

J Cabral, D Vidaurre, P Marques, R Magalhães… - Scientific reports, 2017 - nature.com
Growing evidence has shown that brain activity at rest slowly wanders through a repertoire
of different states, where whole-brain functional connectivity (FC) temporarily settles into …

Association of socioeconomic status with dementia diagnosis among older adults in Denmark

JD Petersen, S Wehberg, A Packness… - JAMA network …, 2021 - jamanetwork.com
Importance Low socioeconomic status (SES) has been identified as a risk factor for the
development of dementia. However, few studies have focused on the association between …

Measuring resilience and resistance in aging and Alzheimer disease using residual methods: a systematic review and meta-analysis

DI Bocancea, AC van Loenhoud, C Groot, F Barkhof… - Neurology, 2021 - AAN Enterprises
Background and Objective There is a lack of consensus on how to optimally define and
measure resistance and resilience in brain and cognitive aging. Residual methods use …

[HTML][HTML] Translational research on reserve against neurodegenerative disease: consensus report of the International Conference on Cognitive Reserve in the …

R Perneczky, G Kempermann, AD Korczyn… - BMC medicine, 2019 - Springer
Background The concept of reserve was established to account for the observation that a
given degree of neurodegenerative pathology may result in varying degrees of symptoms in …

Influence of cognitive reserve on cognitive trajectories: role of brain pathologies

X Li, R Song, X Qi, H Xu, W Yang, M Kivipelto… - Neurology, 2021 - AAN Enterprises
Background and Objectives Evidence on the association of cognitive reserve (CR) with the
cognitive trajectories is limited. We aimed to examine the influence of CR indicator on …

[HTML][HTML] Selecting the most important self-assessed features for predicting conversion to mild cognitive impairment with random forest and permutation-based methods

J Gómez-Ramírez, M Ávila-Villanueva… - Scientific reports, 2020 - nature.com
Alzheimer's Disease is a complex, multifactorial, and comorbid condition. The asymptomatic
behavior in the early stages makes the identification of the disease onset particularly …

A systematic review for functional neuroimaging studies of cognitive reserve across the cognitive aging spectrum

M Anthony, F Lin - Archives of Clinical Neuropsychology, 2018 - academic.oup.com
Objective Cognitive reserve has been proposed to explain the discrepancy between clinical
symptoms and the effects of aging or Alzheimer's pathology. Functional magnetic resonance …

Genetic risk of dementia mitigated by cognitive reserve: a cohort study

S Dekhtyar, A Marseglia, W Xu… - Annals of …, 2019 - Wiley Online Library
Objective We investigated whether cognitive reserve modifies the risk of dementia
attributable to apolipoprotein ε4 (APOE‐ε4), a well‐known genetic risk factor for dementia …